Month: August 2020

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Chloro[l ,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (487.59 mg, 0.25 mmol) and silver triflate (64.2 mg, 0.25 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes. Solution of 1 ,2-bis(diphenylphosphino)benzene (1 1 1.6 mg, 0.25 mmol) in dry THF (5 mL) was added. Reaction mixture was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2CI2 by vapor diffusion of Et20 gave 130 mg (49.6%) of white needle crystals. Structure confirmed by 1H-NMR spectrum of [(IPR)Cu(dppbz)]OTf (CDCb, 400MHz).

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Synthesis of [(SIMes)CuBr]. In an oven-dried vial, copper(I) bromide (0.522 g, 3.63 mmol), SIMes.HCl (0.86 g, 2.52 mmol) and sodium tert-butoxide (0.243 g, 2.52 mmol) were loaded inside a glovebox and stirred in dry THF (18 mL) overnight at room temperature outside of the glovebox. After filtration of the reaction mixture through a plug of Celite, the filtrate was mixed with hexane to form a precipitate. A second filtration afforded 0.808 g (71% yield) of the title complex as an off-white solid.Spectroscopic and analytical data for [(SIMes)CuBr]: 1H NMR (300 MHz, [D6]acetone): delta=7.01 (s, 4H, HAr), 4.16 (s, 4H, NCH2), 2.37 (s, 12H, ArCH3), 2.29 (s, 6H, ArCH3); 13C NMR (75 MHz, CDCl3): delta=202.6 (C, NCN), 138.5 (C, CAr), 135.3 (CH, CAr), 135.0 (C, CAr), 129.7 (CH, CAr), 51.0 (CH2, NCH2), 21.0 (CH3, ArCH3), 18.0 (CH3, ArCH3); Elemental analysis calcd for C21H26BrCuN2 (449.89): C, 56.06; H, 5.83; N, 6.23. Found: C, 55.98; H, 5.64; N, 6.21%.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various.

Reference£º
Patent; Institut Catala d’Investigacio Quimica; Institucio Catalana de Recerca i Estudis Avancats; US2009/69569; (2009); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,as a common compound, the synthetic route is as follows.

In a dry double-mouth bottle to place Ir – 3 (0.0796 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.069 g, and the yield is 50%.

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

7787-70-4, Copper(I) bromide is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

CuI (0.190 g, 1 mmol) was dissolved in acetonitrile (6 ml)at room temperature, followed by the addition of a solution of Hdpt (0.112 g, 0.5 mmol) in acetonitrile (8 ml) with vigorous magnetic stirring in a 25 ml Parr Teflon-lined stainless steel vessel. The mixture was heated for 3 days at 150 C and then cooled to room temperature at a rate of10 C/h.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various.

Reference£º
Article; Hu, Sheng; Lin, DianRong; Xie, ZhenMing; Zhou, ChangXia; He, WenXi; Yu, FangYong; Transition Metal Chemistry; vol. 40; 6; (2015); p. 623 – 629;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

14172-91-9, 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II) is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Under the protection of nitrogen, 0.14 mmol of the corresponding 5,10,15,20-tetrakis(4-R-phenyl)porphyrin copper(II)complex was dissolved in 16 ml of CHCl3, to which 0.75 ml of DMFwas added with magnetic stirring. The solution was cooled to 0 Cin an ice bath, and then 0.56 ml of phosphoryl chloride (POCl3) wasslowly added within 20 min. The ice bath was removed and stirringwas continued at room temperature for 1 h, and the solution wascontinuously stirred and heated at 70 C for 24 h. Then 3.606 g ofNaAc and 14.4 ml of distilled water were added in an ice bath andstirring for another 1 h. After separation of the aqueous layer, theorganic layer was washed with 10 ml of distilled water for 3 times,then dried over anhydrous magnesium sulfate and filtered. Thesolvent was removed by rotary evaporation at low temperature toafford a crude product. The crude product was dissolved indichloromethane and subjected to column chromatography overneutral alumina with dichloromethane/petroleum ether (v/v 3:1)as the eluent. The third coloured bandwas collected and the solventwas removed by rotary evaporation to afford a purple powder.

The synthetic route of 14172-91-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Wu, Zhen-Yi; Yang, Sheng-Yan; Journal of Molecular Structure; vol. 1188; (2019); p. 244 – 254;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7787-70-4,Copper(I) bromide,as a common compound, the synthetic route is as follows.

Direct route A round-bottomed flask equipped with a stirring bar was charged with the ligand, SSBn (0.1503g; 0.383mmol) and acetonitrile (10mL) to give a white milky suspension. Anhydrous CuBr (0.0555g, 0.38mmol) was added in one portion under vigourous stirring to give a white suspension which became briefly transparent after a few minutes. The mixture was stirred overnight to give an off-white precipitate; it was sonicated for a few seconds and further stirred for 30min. Diethyl ether (10mL) was added and stirring was continued for 5min to give the product as a white powder which was filtered, washed with diethyl ether (5mL) and dried in air (0.1802g, 0.334mmol, 88%).Sulfur insertion route [CuBr(CSBn)]2 (103mg, 0.102mmol) was partially dissolved in acetonitrile (20mL) in a Schlenk flask. To this was added an excess of sulfur (66mg, 2mmol per sulfur). The mixture was stirred at 70C for 5h after which time the mixture was diluted with 10mL of acetonitrile and filtered. The residue was extracted with acetonitrile (2¡Á10mL). The solvent of the combined organic phases was removed by oil pump vacuum and the off-white solid dried under reduced pressure. Yield=72.6mg (0.135mmol, 66%). 1H NMR (300MHz, DMSO-d6): delta=5.22 (s, 4H, PhCH2), 6.66 (s, 2H, NCH2N), 7.32 (s, 10H, 2¡Á C6H5), 7.50 (overlapping signal, 2H, CH=CH), 7.70 (overlapping signal, 2H, CH=CH). 13C{1H} NMR (DMSO-d6, 100MHz) delta 50.3 (CH2Ph), 56.2 (NCH2N), 118.9 (CHCH), 119.2 (CHCH), 127.9 (overlapping, m/p-C6H5), 128.6 (o-C6H5), 135.9 (i-C6H5), 159.4 (C=S). IR (cm-1): 3390.3, 3092.1, 1569.7, 1495.9, 1451.8, 1408.1, 1231.2, 1190.4, 959.6, 704.5, 671.6. MS (ESI+), m/z 991 [Cu2(SSBn)2Br]+, 847 [Cu(SSBn)2]+, 455. [Cu(SSBn)]+. Elemental analysis: Calc. for C21H20BrCuN4S2: C: 47.06; H: 3.76; N: 10.45. Found: C: 46.96; H: 3.81; N: 10.40.

7787-70-4 Copper(I) bromide 24593, acopper-catalyst compound, is more and more widely used in various.

Reference£º
Article; Slivarichova, Miriam; Correa ?da Costa, Rosenildo; Nunn, Joshua; Ahmad, Ruua; Haddow, Mairi F.; Sparkes, Hazel A.; Gray, Thomas; Owen, Gareth R.; Journal of Organometallic Chemistry; vol. 847; (2017); p. 224 – 233;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Copper(II) trifluoromethanesulfonate (5 g, 14 mmol) was dissolved in methanol (25 mL). Pyridine(12 mL, 149 mmol) was added dropwise (exothermic reaction was observed) and the reaction mixturewas stirred for 30 min. The mixture was left at ambient temperature for 1 h and thereafter in fridge (at5 C) overnight. The blue crystalline precipitate was filtered off, recrystallized from 20% Py in MeOHand dried under a stream of air affording the desired product [56]. Yield 8.5 g, 91%Appearance blue solidMolecular formula C22H20CuF6N4O6S2Molar mass 678.08042Anal.Calcd for C22H20CuF6N4O6S2: C, 38.97; H, 2.97; N, 8.26. Found: C,39.1 < 0.1; H, 3.16 0.09; N, 8.33 0.01. 34946-82-2 Copper(II) trifluoromethanesulfonate 2734996, acopper-catalyst compound, is more and more widely used in various. Reference£º
Article; Zarrad, Fadi; Zlatopolskiy, Boris D.; Krapf, Philipp; Zischler, Johannes; Neumaier, Bernd; Molecules; vol. 22; 12; (2017);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,as a common compound, the synthetic route is as follows.

In a dry double-mouth bottle to place Ir – 3 (0.0796 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.069 g, and the yield is 50%.

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

13395-16-9, Bis(acetylacetone)copper is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: In a typical synthesis of Cu40Ag60, 0.45mmol Cu(acac)2 and 0.35 Ag (ac) was mixed with 3mL of OAm, 1 mL of OAc and 11mL of ODE. All synthesis was conducted in a four-necked glass reactor allowing the precise temperature control and inert gas atmosphere under dark conditions. Firstly, the mixture was heated to 60C and kept at this temperature for 10min. Then, the mixture was heated to 180C and kept at this temperature for 30min before it was cooled down to room temperature. After cooling, the resultant reaction mixture was collected with hexane (2mL) and the NPs were separated by centrifugation (8500rpm, 12min) after adding isopropanol (40mL). To further purify the yielded CuAg NPs, the product was centrifuged (8500rpm, 12min) one more time with ethanol (40mL). Finally, the remaining product was dispersed in hexane (10mL) for further use. By using the same recipe and varying metal precursor amounts, two different compositions of CuAg NPs were synthesized. Reductive mixing of 0.3mmol Cu(acac)2 and 0.5 Ag(ac) resulted in Cu30Ag70 NPs and mixing 0.6mmol Cu(acac)2 with 0.4 Ag (ac) led to Cu60Ag40. Synthesis of Ag NPs was conducted with the same recipe without using Cu precursor.

As the paragraph descriping shows that 13395-16-9 is playing an increasingly important role.

Reference£º
Article; Balkan, Timucin; Kuecuekkececi, Hueseyin; Kaya, Sarp; Metin, Oender; Zarenezhad, Hamaneh; Journal of Alloys and Compounds; vol. 831; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”