Month: September 2020

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

A yellow solution of 168.0 mg (0.736 mmol) of 2b in toluene (10 mL) was added to a green CH3CN solution (20 mL) containing 105.6 mg (0.736 mmol) CuBr with stirring at ambient temperature. The reaction mixture was allowed to stir overnight forming a dark green precipitate. The solution was filtered, and the precipitate washed with cold MeOH (5 mL) and dried under vacuum (57.9 mg, 17% yield). 1H and 13C{1H} NMR spectra could not be recorded due to strong paramagnetic properties of complex. FTIR (KBr) 3425, 3056, 3006, 2918, 1627, 1593, 1466, 1436, 1300, 1269, 1236, 1201, 1157, 1106, 1092, 1069, 1046, 967, 958, 914, 849, 774, 767, 744, 694, 652, 567, 543, 501, 458, 417 cm-1. Anal. Calc’d. for C13H12Br2CuN2S: C = 34.57%, H = 2.68%, N = 6.20%. Found: C = 34.17%, H = 3.36%, N = 6.44%. UV-vis (DMF, 0.050 mg/mL) lambdamax (epsilon) = 266 (7.6 * 103), 353., 7787-70-4

The synthetic route of 7787-70-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Cross, Edward D.; Ang, M. Trisha C.; Richards, D. Douglas; Clemens, Amy C.; Muthukumar, Harshiny; McDonald, Robert; Woodfolk, London; Ckless, Karina; Bierenstiel, Matthias; Inorganica Chimica Acta; vol. 481; (2018); p. 69 – 78;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact.7787-70-4, Copper(I) bromide it is a common compound, a new synthetic route is introduced below.7787-70-4

A mixture of CuBr (28.7mg, 0.2mmol) and dppp (82.5mg, 0.2mmol) with an excess of batho (66.5mg, 0.2mmol) were dissolved in CH2Cl2 (5mL) and CH3OH (5mL) solution, stirred at room temperature for 6h. The insoluble residues were removed by filtration, and the filtrate was evaporated slowly at room temperature to yield yellow crystalline products. Yield: 80%. Anal. Calc. for C53H50BrCuN2O2P2: C, 66.84; H, 5.29; N, 2.94. Found: C, 66.97; H, 5.15; N, 2.88%. IR (KBr disc, cm-1): 3378s, 3048w, 2858w, 2580w, 1616w, 1556m, 1515m, 1433s, 1414m, 1229m, 1026s, 998w, 767m, 740s, 698vs, 513s, 482m. 1H NMR (600MHz, CDCl3, 298K): delta 7.87-8.98 (d, 6H, batho CH), 7.56-7.68 (m, 10H, batho CH), 7.41-7.24 (m, 20H, dppp CH), 2.91-2.81 (m, 4H, CH2), 2.78-2.63 (m, 2H, CH2); 31P NMR (400MHz, CDCl3, 298K): -12.25, -14.84.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) bromide,belong copper-catalyst compound

Reference£º
Article; Yu, Xiao; Fan, Weiwei; Wang, Guo; Lin, Sen; Li, Zhongfeng; Liu, Min; Yang, Yuping; Xin, Xiulan; Jin, Qionghua; Polyhedron; vol. 157; (2019); p. 301 – 309;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(II) trifluoromethanesulfonate, cas is 34946-82-2, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,34946-82-2

To a solution of 6.90 g (18.5 mmol) of 5′-bromo-3′-nitro-3,4,5,6-tetrahydro-2H- [l,2′]bipyridinyl-4-yl)-acetic acid in dimethylsulfoxide (100 mL) is added 4.5 mL (41 mmol) of dimethylethylenediamine followed by 4.0 g (39 mmol) of sodiummethanesulfinate and 5.5 g (19 mmol) of copper (II) triflate. The mixture is heated to 130 C for lhour then cooled to room temperature. The mixture is diluted with water and stirred overnight during which time a solid precipitates from solution. The yellow solid is collected by filtration, washed with water and dried on the filter pad to provide 5.00 g (72.6%) of (5′-methanesulfonyl-3′-nitro-3,4,5,6-tetrahydro-2H-[l,2′]bipyridinyl-4-yl)- acetic acid ethyl ester.

34946-82-2 is used more and more widely, we look forward to future research findings about Copper(II) trifluoromethanesulfonate

Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; GINN, John David; SORCEK, Ronald John; TURNER, Michael Robert; WU, Di; WU, Frank; WO2011/84985; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14172-91-9,5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),as a common compound, the synthetic route is as follows.,14172-91-9

To a stirred solution of (meso-tetraphenylporphyrinato)copper(II) (1c; 237 mg, 0.35 mmol) inCHCl3 (530 mL) at room temperature, a solution of 25% aqueous nitric acid (freshly prepared fromfuming yellow HNO3, d = 1.52; large excess, 140 mL, 637 mmol) was added dropwise during ca5 min. The reaction mixture was intensively stirred under argon in a round-bottomed ask, protectedagainst light, for 30-40 min with TLC monitoring (CHCl3/n-hexane-1:1). Then, the mixture waspoured into aqueous solution of 5% NaHCO3 (200 mL), and shaken carefully in a separatory funnel.The separated organic layer was washed with water (4 200 mL), and dried with anhydrousMgSO4/Na2CO3. After evaporating the solvent, the residue was subjected to column chromatography(eluent: CHCl3/n-hexane1:1) to give (2-nitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (2c; 71 mg, 28%) and a mixture of dinitro-substituted isomers (150 mg, 56%). Thedinitro-isomers were separated on preparative TLC (CHCl3/n-hexane-1:1, four times developed),allowing isolation of: (a) (2,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3ca; 40 mg,15%); (b) (3,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3cb; 35.5 mg, 13%); (c)(2,8-dinitro-5,10,15,20-tetra-phenylporphyrinato)copper(II) (3cc) contaminated with small amountsof (3,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3cb) (30 mg, yield-ca 10%). 3cc can befurther purified by preparative TLC.

14172-91-9 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II) 3722750, acopper-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Mikus, Agnieszka; Rosa, Mariusz; Ostrowski, Stanis?aw; Molecules; vol. 24; 5; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

The molar ratio of Cu (CF3SO3) 2 and 4- (3- (4H-1,2,4-triazol-4-yl) phenyl) -4H-1,2,4-triazole) (L)For 1: 1;L (0.0424 g, 0.2 mmol), Cu (CF3SO3) 2 (0.0691 g, 0.2 mmol), H2O (6 mL)CH3CN (4 mL), water heat 100 oC three days later slowly to room temperature.After the opening, there are yellow rod-like crystals suitable for X-ray single crystal diffraction analysis. Yield: 35% (based on L calculation).

34946-82-2, The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Tianjin Normal University; Wang, Ying; (11 pag.)CN104557984; (2017); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,as a common compound, the synthetic route is as follows.,578743-87-0

Chloro[l,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (195.1 mg, 0.4 mmol) and silver triflate (102.7 mg, 0.4 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes.Solution of 2,2′-bipyridine (62.4 mg, 0.4 mmol) in dry THF (5 mL) was added. Reaction mixture turned orange and was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2CI2 by vapor diffusion of EtaO gave 215 mg (70.9%) of orange crystals. Anal, calcd. forC38H44CUF3N4O3S: C, 60.26; H, 5.86; N, 7.40; Found: C, 60.18; H, 5.82; N, 7.38. Structure was confirmed by iH-NMR spectrum of [(IPR)Cu(bipy)]OTf (CDCb, 400MHz).

As the paragraph descriping shows that 578743-87-0 is playing an increasingly important role.

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34946-82-2,Copper(II) trifluoromethanesulfonate,as a common compound, the synthetic route is as follows.

Ligand L2/L2? (15.2 mg, 63 mumol) was dissolved in ethylacetate (5 mL) and a solution of Cu(OTf)2 (11.4 mg, 31.5mumol) in ethyl acetate (3 mL) was added. The blue precipitatewas isolated by filtration with suction and dried at air;yield: 26 mg (98%). Crystals suitable for X-ray diffractionanalysis were obtained when a solution of the precipitatein the necessary amount of ethyl acetate was concentratedby slow evaporation. M.p. 255.5-256.5C. – IR (KBr): IR(KBr): = 3259 s br (NH), 3151 w, 1643 m, 1591 s, 1500 m,1285 vs, 1243 vs, ~1228 sh, 1159 s, 1028 vs, 720 m, 636 s,574 w, 518 m cm-1. – MS ((+)-MALDI-TOF): m/z (%) = 694.15(100) [M-CF3SO3]+, 1539.24 (8) [2 [CuL2L2?(OTf)2]-OTf]. -Anal. for C28H30CuF6N10O6S2 (844.27), water-free sample:calcd. C 39.83, H 3.58, N 16.59; S 7.59; found C 39.62, H 3.41,N 16.64, S 7.61., 34946-82-2

The synthetic route of 34946-82-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Schroeder, Sven; Frey, Wolfgang; Maas, Gerhard; Zeitschrift fur Naturforschung, B: Chemical Sciences; vol. 71; 6; (2016); p. 683 – 696;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

34946-82-2, Copper(II) trifluoromethanesulfonate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A methanolic solution of ligand trans-cyclohexane-1,2-diamine(0.1142 g, 1 mmol) was added dropwise to a clear solution ofCopper(II) trifluoromethanesulfonate (0.1808 g, 0.5 mmol) inmethanol (10 mL). The resultant solution was stirred at roomtemperature for 6 h to produce a dark blue coloured solution. Thediffraction quality crystals of the titled complex were obtaineddirectly by slow evaporation of the deep bluish methanolic solutionat room temperature. Yield: 0.272 g, 75%, m.p: 258 C, Anal. Calc. forC14H32CuF6N4O8S2: C, 26.86; H, 5.15; N, 8.95. Found: C, 26.54; H,5.32, N, 8.78. Selected FT-IR (KBr), cm1: n(NH2) 3332e3279, n(CH2)2967e2861, n(OH) 3463, n(CueN) 628, n(CueO) 514. UVeVis [lmax(nm), epsilon (L mol1 cm1)]: 243 (8940), 548 (89)., 34946-82-2

As the paragraph descriping shows that 34946-82-2 is playing an increasingly important role.

Reference£º
Article; Agrahari, Bhumika; Layek, Samaresh; Kumari, Shweta; Anuradha; Ganguly, Rakesh; Pathak, Devendra D.; Journal of Molecular Structure; vol. 1134; (2017); p. 85 – 90;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO290,mainly used in chemical industry, its synthesis route is as follows.,34946-82-2

To a yellow-brown solution of L1 (60 mg, 0.09 mmol) in THF (3 mL)was added a blue solution of [Cu(OTf)2] (36 mg, 0.09 mmol) at roomtemperature. Upon addition the solution colored to dark green. Themixture solution was stirred for 8 h and after filtered, 20 mL of diethylether were then added to the filtrate to precipitate a green solid. Thesolvents were removed by filtration and the residue was washed withether (3¡Á5 mL) and dried in vacuum to yield product 3 as a blue-greenpowder. The formulation of 3 was deduced from elemental analysis asbeing [Cu(H2O)2(L1)](OTf)2, H2O. Yield: 50 mg, 56%. Crystals suitablefor a X-ray diffraction study were obtained by slow vapor diffusion ofEt2O into a CH3CN solution of 3 in a sealed tube. IR (solid, cm-1):nu(NH) 3334 (w), nu(CO) 1654 (w), nu(CF) 1027 (s). UV-Vis (MeCN) lambdamax,nm (epsilon, M-1cm-1): 257 (28110), 284 (26400), 666 (51), EPR (9.30 GHz;CH3CN; 150 K): g//=2.27, g?=2.05, A//=166 G. Elemental analysis calcd (%) for C39H29CuF6N7O8S2. 1 H2O: C, 45.93; H, 3.46; N, 9.62.Found: C, 45.72; H, 3.17; N, 9.23.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) trifluoromethanesulfonate,belong copper-catalyst compound

Reference£º
Article; Ayad, Massinissa; Schollhammer, Philippe; Le Mest, Yves; Wojcik, Laurianne; Petillon, Francois Y.; Le Poul, Nicolas; Mandon, Dominique; Inorganica Chimica Acta; vol. 497; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(I) bromide, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route. 7787-70-4

A solution of (4-diphenylphosphino)phenanthridine (0.023 g,0.063 mmol) in CH2Cl2 (3 mL) was added drop-wise to a suspensionof CuBr (0.089 g, 0.063 mmol) in CH2Cl2 (3 mL) with constantstirring. The reaction mixture was stirred for overnight at roomtemperature. Then the reaction mixture was filtered through smallplug of Celite and dried under vacuum to give an orange solid.Yield = 0.022 g (71%).

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(I) bromide,belong copper-catalyst compound

Reference£º
Article; Mondal, Rajarshi; Giesbrecht, Patrick K.; Herbert, David E.; Polyhedron; vol. 108; (2016); p. 156 – 162;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”