Day: November 21, 2022

Mukhopadhyay, Sukanya published the artcileMOCVD of copper films from bis(ethyl-3-oxo-butanoato)copper(II). Experiment and thermodynamic analysis, Safety of Copper(II) ethylacetoacetate, the publication is Proceedings – Electrochemical Society (2003), 1275-1283, database is CAplus.

Thin films of Cu were grown on SiO₂/Si(100) substrates by metalorganic chem. vapor deposition (MOCVD) using the precursor, bis(ethyl-3-oxo-butanoato)Cu(II), and characterized by x-ray diffraction and Auger electron spectroscopy. The anal.-determined composition of Cu films grown by chem. vapor deposition is found to match well with that predicted by thermodn. anal. based on the minimization of the total Gibbs free energy of the expected reaction products. This was based on an enumeration of reaction products using mass spectrometric anal. of the precursor and chem. reasoning. Such thermodn. anal. of metalorganic chem. vapor deposition processes can, therefore, be helpful in determining deposition conditions that yield films of desired quality.

Proceedings – Electrochemical Society published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Safety of Copper(II) ethylacetoacetate.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mane, Anil published the artcileCVD of thin films of copper and cobalt from different precursors: growth kinetics and microstructure, Synthetic Route of 14284-06-1, the publication is Materials Research Society Symposium Proceedings (2001), G6.11.1-G6.11.6, database is CAplus.

The authors have studied the growth of thin films of Cu and Co by CVD using the β-diketonate complexes of the metals, viz., the resp. acetylacetonates, dipivaloylmethanates, and ketocarboxylates. Film growth rate was measured as a function of CVD parameters such as substrate temperature and reactor pressure. Film microstructure was examined by optical microscopy, XRD, SEM, and STM. Elec. resistivity was measured as a function of temperature and film thickness. Film microstructure is a function of the mol. structure of the precursor and of the other growth parameters. For example, Cu films from Cu(II) ethylacetoacetate comprise uniform, fine grains which result in bulk elec. conductivity at a thickness ≥75nm. Though grown under nearly the same conditions, Cu films from Cu(II) dipivaloylmethanate are porous, with faceted, large crystallites. Co films from Co(II) acetylacetonate are x-ray amorphous even at a deposition temperature of 450°. It is possible, by choosing CVD parameters, to obtain metal films with microstructures appropriate to devices and to structures of very small dimensions.

Materials Research Society Symposium Proceedings published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Synthetic Route of 14284-06-1.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Raman, N. published the artcileSynthesis, structural and antimicrobial activities of some phenylhydrazone derivatives of metal β-diketonates/β-ketoesters, Product Details of 0, the publication is Asian Journal of Chemistry (1997), 9(2), 183-186, database is CAplus.

Phenylhydrazone derivatives of Cu(II), Ni(II), Co(II) and Co(III) complexes of β-diketones/β-keto esters were prepared These complexes I [R¹ = R² = Me, M = Cu(II), Co(II); R¹ = OEt, R² = Me, M = Cu(II), Ni(II)] as well as a Co(III) tris(β-diketonate) complex were characterized by elemental analyses, IR, UV spectral data, molar conductance and magnetic susceptibility. The complexes exhibited antimicrobial activity against the gram-pos. Escherichia coli. The complexes had minimal inhibitory concentration (MIC) values < 10 μg/10 μL for their in vitro antifungal activity against candida albicans. The presence of an azomethine moiety and the chelation effect of the ligand with central metal atom enhance the antimicrobial activities.

Asian Journal of Chemistry published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Product Details of 0.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Fera, Daniela published the artcileIdentification and Characterization of Small Molecule Antagonists of pRb Inactivation by Viral Oncoproteins, Related Products of copper-catalyst, the publication is Chemistry & Biology (Oxford, United Kingdom) (2012), 19(4), 518-528, database is CAplus and MEDLINE.

The retinoblastoma protein pRb is essential for regulating many cellular activities through its binding and inhibition of E2F transcription activators, and pRb inactivation leads to many cancers. pRb activity can be perturbed by viral oncoproteins including human papillomavirus (HPV) that share an LxCxE motif. Because there are no treatments for existing HPV infection leading to nearly all cervical cancers and other cancers to a lesser extent, we screened for compounds that inhibit the ability of HPV-E7 to disrupt pRb/E2F complexes. This lead to the identification of thiadiazolidinedione compounds that bind to pRb with mid-high nanomolar dissociation constants, are competitive with the binding of viral oncoproteins containing an LxCxE motif, and are selectively cytotoxic in HPV-pos. cells alone and in mice. These inhibitors provide a promising scaffold for the development of therapies to treat HPV-mediated pathologies.

Chemistry & Biology (Oxford, United Kingdom) published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Related Products of copper-catalyst.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mun, Yangun published the artcileMetal-containing initiator systems. XXXVI. Synthesis of block copolymer of methyl acrylate and α-methylbenzyl methacrylate with binary initiator system of cobaltocene and bis(ethyl acetoacetato)copper(II), COA of Formula: 0, the publication is Journal of Macromolecular Science, Chemistry (1984), A21(11-12), 1535-46, database is CAplus.

Block copolymerization of Me acrylate (I) and (DL)-α-methylbenzyl methacrylate (II) with a cobaltocene  [1277-43-6]-Cu(AcCH₂CO₂Et)₂  [14284-06-1] initiator system at 25° in MeCN was studied. The mol. weight of I polymer [9011-14-7] increased with time in the early stages of polymerization Although II polymer [25085-84-1] was also prepared, asym. selective polymerization was not induced by the presence of (-)-sparteine. I–II block copolymer [92542-26-2] was prepared in up to 90% yield. I–II block copolymer yield depended on the prepolymerization time of I with this system. The block copolymer was characterized by IR, NMR, and gel-permeation chromatog.

Journal of Macromolecular Science, Chemistry published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, COA of Formula: 0.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mun, Yang Un published the artcileMetal-containing initiator systems. XXXIII. Polymerization of vinyl monomers initiated by binary system of bis(ethyl acetoacetato)copper(II) and sodium tetraphenylborate, Formula: 0, the publication is Journal of Macromolecular Science, Chemistry (1984), A21(5), 645-60, database is CAplus.

The bis(ethyl acetoacetato)copper(II) (I) [14284-06-1]–Na tetraphenylborate (II) [143-66-8] binary system effectively initiated the radical polymerizations of Me methacrylate (III) [80-62-6] and Me acrylate  [96-33-3]. The overall activation energy of III polymerization with I–II in Me₂CO was calculated to be 15.8 kcal/mol compared to 17.6 kcal/mol for III polymerization with I alone. The polymerization rate was represented by R_p = k[I]^0.5[II]^0.5[III]^2.5. The high order for III concentration suggested participation of the monomer in the initiation process. This was supported by examination of visible and ESR spectra of the I–II–III-Me₂CO system. Reduction of Cu(II) to Cu(I) was indicated by the ESR spectra. The spin-trapping technique was applied to the I–II–III system, and an initiation mechanism for the I–II binary system was discussed.

Journal of Macromolecular Science, Chemistry published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Formula: 0.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mun, Yang Un published the artcileMetal-containing initiator systems. XXXII. Polymerization of vinyl monomers initiated by the binary system of bis(acetylacetonato)cobalt(II) and sodium tetraphenylborate, Computed Properties of 14284-06-1, the publication is Memoirs of the Faculty of Engineering, Osaka City University (1983), 149-59, database is CAplus.

NaBPh₄ (I) [143-66-8] accelerated the polymerization of vinyl monomers in the presence of transition-metal chelates, especially bis(acetylacetonato)cobalt (II) [14024-48-7]. A rate equation for the polymerization of Me methacrylate (III) [80-62-6] with the I–II catalyst system was formulated and an overall activation energy of 9.6 kcal/mol determined The presence of I accelerated the polymerization of III in the presence of Co²⁺, Cu²⁺, and Co³⁺ chelates but had little no effect with Mn²⁺, Mn³⁺, TiO²⁺, and Ni²⁺ chelates. Co²⁺ salts showed lower polymerization activity than the II complex, while H₂O 18-crown-6  [17455-13-9], and p-benzoquinone  [106-51-4] inhibited the polymerization process. The rate of polymerization of III using the I–II catalyst system was 2nd order with respect to III and proportional to the square roots of the concentrations of both initiators. An initiation mechanism for this system was suggested based on spin-trapping techniques.

Memoirs of the Faculty of Engineering, Osaka City University published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Computed Properties of 14284-06-1.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mun, Yang Un published the artcileMetal-containing initiator systems. 34. Polymerization of vinyl monomers initiated by the binary system cobaltocene/bis(ethyl acetoacetato)copper(II), Related Products of copper-catalyst, the publication is Makromolekulare Chemie (1984), 185(8), 1493-505, database is CAplus.

The effect of some metallocenes such as ferrocene  [102-54-5], nickelocene  [1271-28-9], and cobaltocene (I) [1277-43-6], on the vinyl polymerization initiated with bis(Et acetoacetato)copper(II) (II) [14284-06-1] was investigated. I exerted a markedly accelerating effect on the polymerization of methyl methacrylate (III) [80-62-6] with II. The polymerization of III with I–II system at 50° was affected by the solvent used. The results of copolymerization of III with styrene and the effect of hydroquinone on the polymerization of III with I–II showed that the polymerization proceeds via a radical mechanism. The polymerization of III with I–II was studied kinetically in acetone. The overall activation energy of the polymerization was calculated to be 20.6 kcal/mol. This value was somewhat higher than that (17.6 kcal/mol) obtained for the polymerization of III with II alone. The polymerization rate (R_p) is represented by the equation: R_p = k[I]^0.5[II]^0.2[III]^1.3. The high order in monomer concentration suggests a participation of the monomer in the initiation process. This is supported by the examination of the ESR spectrum of the system I–II–III-acetone, where reduction of Cu(II) to Cu(I) occurs. To elucidate the initiation mechanism, the spin trapping technique was applied to the system I–II-Me acrylate. From these results, an initiation mechanism for the binary initiator system I–II is proposed and discussed.

Makromolekulare Chemie published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Related Products of copper-catalyst.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Mun, Yan Un published the artcileMetal-containing initiator systems. 35. Synthesis of block copolymers by using the binary initiator system cobaltocene/bis(ethyl acetoacetato)copper(II), Name: Copper(II) ethylacetoacetate, the publication is Makromolekulare Chemie (1984), 185(8), 1507-16, database is CAplus.

Polymerization of methyl methacrylate (I) [80-62-6] with the binary initiator system cobaltocene  [1277-43-6]–bis(Et acetoacetato)copper(II) [14284-06-1] was studied kinetically at 25° in acetonitrile. The relationship between yield and mol. weight of the resulting I polymer was suggestive of a living polymerization character in this system. The synthesis of block copolymers [25034-86-0] of I with styrene (II) was attempted by adding II as the second monomer to the polymerization system of I. The block copolymer was formed in a yield of 20% where I was polymerized for 1 day, while the yield went up to 80% when the I polymerization was carried out for 3 days. The resulting block copolymer was characterized by IR spectroscopy and gel-permeation chromatog.

Makromolekulare Chemie published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Name: Copper(II) ethylacetoacetate.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Krammer, B. published the artcileA novel screening assay for hydroxynitrile lyases suitable for high-throughput screening, Computed Properties of 14284-06-1, the publication is Journal of Biotechnology (2007), 129(1), 151-161, database is CAplus and MEDLINE.

Hydroxynitrile lyases (Hnls) are important biocatalysts for the synthesis of optically pure cyanohydrins, which are used as precursors and building blocks for a wide range of high price fine chems. Although two Hnl enzymes, from the tropical rubber tree Hevea brasiliensis and from the almond tree Prunus amygdalus, are already used for large scale industrial applications, the enzymes still need to be improved and adapted to the special demands of industrial processes. In many cases directed evolution has been the method of choice to improve enzymes, which are applied as industrial biocatalysts. The screening procedure is the most crucial point in every directed evolution experiment Herein, we describe the successful development of a novel screening assay for Hnls and its application in high-throughput screening of Escherichia coli mutant libraries. The new assay allows rapid screening of mutant libraries and facilitates the discovery of improved enzyme variants. Hnls catalyze the cleavage of cyanohydrins to hydrocyanic acid and the corresponding aldehyde or ketone. The enzyme assay is based on the detection of hydrocyanic acid produced, making it an all-purpose screening assay, without restriction to any kind of substrate. The gaseous HCN liberated within the Hnl reaction is detected by a visible colorimetric reaction. The facile, highly sensitive and reproducible screening method was validated by identifying new enzyme variants with novel substrate specificities.

Journal of Biotechnology published new progress about 14284-06-1. 14284-06-1 belongs to copper-catalyst, auxiliary class Copper, name is Copper(II) ethylacetoacetate, and the molecular formula is 0, Computed Properties of 14284-06-1.

Referemce:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660968/,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”