Month: February 2023

Copper-catalysed synthesis of trifluoromethyl allenes via fluoro-carboalkynylation of alkenes was written by Wang, Mengning;Wang, Qiuzhu;Ma, Mengtao;Zhao, Binlin. And the article was included in Organic Chemistry Frontiers in 2022.Related Products of 34946-82-2 This article mentions the following:

A copper-catalyzed synthesis of trifluoromethyl allenes utilizing readily available feedstocks under mild and environmentally friendly conditions was developed, which provided an operationally simple and practical platform for the preparation of substituted allenes with a broad substrate scope. Mechanistic explorations showed that a radical-mediated fluorocarboalkynylation and base-promoted step-wise isomerization of β-CF₃ alkynes were responsible for the formation of the desired allenes. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Related Products of 34946-82-2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. The copper-mediated C-C, C-O, C-N, and C-S bond formation is a part of one oldest reaction, emphasizing the Ullmann cross-coupling reaction.Related Products of 34946-82-2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

π-Extended Ligands in Two-Coordinate Coinage Metal Complexes was written by Muniz, Collin N.;Schaab, Jonas;Razgoniaev, Anton;Djurovich, Peter I.;Thompson, Mark E.. And the article was included in Journal of the American Chemical Society in 2022.Quality Control of Copper(II) trifluoromethanesulfonate This article mentions the following:

Two-coordinate carbene-M^I-amide (cMa, M^I = Cu, Ag, Au) complexes have emerged as highly efficient luminescent materials for use in a variety of photonic applications due to their extremely fast radiative rates through thermally activated delayed fluorescence (TADF) from an interligand charge transfer (ICT) process. A series of cMa derivatives was prepared to examine the variables that affect the radiative rate, with the goal of understanding the parameters that control the radiative TADF process in these materials. Authors find that blue-emissive complexes with high photoluminescence efficiencies (Φ_PL > 0.95) and fast radiative rates (k_r = 4 x 10⁶ s^-1) can be achieved by selectively extending the π-system of the carbene and amide ligands. Of note is the role played by the increased separation between the hole and electron in the ICT excited state. Anal. of temperature-dependent luminescence data and theor. calculations indicate that the hole-electron separation exerts a primary effect on the energy gap between the lowest-energy singlet and triplet states (ΔE_ST) while keeping the radiative rate for the singlet state relatively unchanged. This interpretation provides guidelines for the design of new cMa derivatives with even faster radiative rates in addition to those with slower radiative rates and thus extended excited state lifetimes. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Quality Control of Copper(II) trifluoromethanesulfonate).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to low toxicity and inexpensive, earth-abundant. Copper nanoparticles can also catalyze the coupling reaction of nitrogen-containing nucleophiles, phenols, thiols, xanthogenates, selenium ruthenium nucleophiles and the like.Quality Control of Copper(II) trifluoromethanesulfonate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper-Catalyzed Dehydrogenative Amidation of Light Alkanes was written by Fuentes, M. Angeles;Gava, Riccardo;Saper, Noam I.;Romero, Erik A.;Caballero, Ana;Hartwig, John F.;Perez, Pedro J.. And the article was included in Angewandte Chemie, International Edition in 2021.HPLC of Formula: 14781-45-4 This article mentions the following:

The functionalization of C-H bonds in light alkanes, particularly to form C-N bonds, remains a challenge. The dehydrogenative coupling of amides with C1-C4 hydrocarbons to form N-alkyl amide products with tBuOOtBu as oxidant, and a copper complex of a phenanthroline-type ligand as catalyst was reported. The reactions occurred in good yields in benzene or supercritical carbon dioxide as solvents. This strategy allowed for the determination of the relative reactivity of these alkane C-H bonds toward this amination process and showed, in contrast to prior work with larger alkanes, that the reactivity correlated with bond dissociation energies. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4HPLC of Formula: 14781-45-4).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, inexpensive and low toxicity. These ligands enable the reaction promoted in mild condition. The reaction scope has also been greatly expanded, rendering this copper-based cross-coupling attractive for both academia and industry. HPLC of Formula: 14781-45-4

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Tf₂O- and Cu(OTf)₂-Assisted Acylamination Reaction of Unactivated Alcohols with Nitriles: A One-Pot P(IV) Activation, Stereoretention in Cycloalkanols and Deprotection Approach was written by Bhat, Mohammad Yaqoob;Ahmed, Sajjad;Ahmed, Qazi Naveed. And the article was included in Journal of Organic Chemistry in 2022.Category: copper-catalyst This article mentions the following:

Described herein is a simple, novel, one-pot acylamination reaction of unactivated alcs. This reaction employs the combination of PCl₃ and triflic anhydride (Tf₂O) or copper triflate Cu(OTf)₂, which serves as a source of P(IV)-activated complex for nitriles to react under the Ritter-type mechanism. The synthetic utility of Tf₂O-promoted reactions was demonstrated by its effectiveness to generate different acylaminated products. By employing Cu(OTf)₂, this method represented a rare example of α-selective acylamination reaction. With chiral cycloalkanols, using the Cu(OTf)₂-promoted procedure, acylaminated products were formed with complete retention of configuration. The synthetic utility of the copper-assisted reaction in acetonitrile was readily demonstrated as a mild deprotection strategy. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Category: copper-catalyst).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, inexpensive and low toxicity. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.Category: copper-catalyst

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

High enantioselectivity is induced by a single monodentate phosphoramidite ligand in iridium-catalyzed asymmetric hydrogenation was written by Giacomina, Francesca;Meetsma, Auke;Panella, Lavinia;Lefort, Laurent;de Vries, Andre H. M.;de Vries, Johannes G.. And the article was included in Angewandte Chemie, International Edition in 2007.Computed Properties of C24H34O2 This article mentions the following:

Stripping a catalyst down to its bare essentials makes a neutral iridium complex, containing only one monodentate phosphoramidite ligand, an efficient catalyst for the enantioselective hydrogenation of α-dehydroamino acids. For example, neutral iridium chiral catalyst [Ir(COD)(L)Cl], where L = (S)-(3,3′-di-tert-butyl-5,5′,6,6′-tetramethyl-1,1′-biphenyl-2,2′-diyl)-N,N-dimethylphosphoramidite (I), is an effective catalyst for the asym. hydrogenation of PhCH:C(NHCOMe)CO₂Me to N-acetylphenylalaninate Me ester. In the experiment, the researchers used many compounds, for example, (S)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol (cas: 205927-03-3Computed Properties of C24H34O2).

(S)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol (cas: 205927-03-3) belongs to copper catalysts. Copper catalyst has received great attention owing to the low toxicity and low cost. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Computed Properties of C24H34O2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Synthesis of ortho-Phosphated (Hetero)Arylamines through Cascade Atherton-Todd Reaction/[3,3]-Rearrangement from Arylhydroxylamines and Dialkyl Phosphites was written by Liu, Xiao;Pei, Jingtai;Gao, Zhiwei;Gao, Hongyin. And the article was included in Organic Letters in 2022.Electric Literature of C2CuF6O6S2 This article mentions the following:

A practical and facile strategy for the synthesis of ortho-phosphated (hetero)arylamines from readily available arylhydroxylamines and dialkyl phosphites via cascade Atherton-Todd reaction/[3,3]-rearrangement was developed. This method is amenable to various arylhydroxylamines such as phenylhydroxylamines, naphthylhydroxylamines, and pyridylhydroxylamines, has mild reaction conditions, is oxidant-free, and has good functional-group compatibility and excellent regioselectivity. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Electric Literature of C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The evolution of transition metal catalysts has attained a stage of civilization that authorizes for an extensive scope of chemical bonds formation partners to be combined efficiently. Copper nanoparticles can catalyze the Ullmann coupling reaction in a wide range of applications.Electric Literature of C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A new family of multinuclear mixed-ligand copper(II) clusters: Crystal structures, magnetic properties and catecholase-like activity was written by Calancea, Sergiu;Reis, Samira G.;Guedes, Guilherme P.;Cassaro, Rafael A. Allao;Semaan, Felipe;Lopez-Ortiz, Fernando;Vaz, Maria G. F.. And the article was included in Inorganica Chimica Acta in 2016.Name: copper(ii)hexafluor-2,4-pentanedionate This article mentions the following:

The authors report a family of mixed-ligand Cu(II) clusters obtained with different nuclearities: (Et₃NH)[Cu₃(μ₃-OH)(μ-dppi)₃(μ-hfac)₃] (1), [Cu₄(μ-dppi)₄(Hdppi)₂(hfac)₄] (2), [Cu₅(μ-O)₂(μ-dppi)(μ-Hdppi)₂(μ-hfac)₃(hfac)₂] (3) and [Cu₆(μ-O)₂(μ-dppi)₂(μ-Hdppi)(μ-hfac)₆] (4), where hfac = hexafluoroacetylacetonate, dppi = diphenylphosphinate and Hdppi = diphenylphosphinic acid. Complexes 3 and 4 are the first examples of Cu(II) clusters containing a μ-oxo O atom and hfac as bridging ligands. The magnetic properties of all compounds showed predominant antiferromagnetic interactions and the magnetic coupling constants were evaluated using an isotropic exchange model based on the spin topol. A spin frustration phenomena was observed for the equilateral cyclic trinuclear complex (1), thus an antisym. exchange term was also considered to fit the exptl. magnetic data. The obtained J values are at -89 cm^-1 to 1.7 cm^-1 and were interpreted based on structural features. The electrochem. properties and catalytic activity of complexes 1 and 2 were studied and compared with the [Cu(hfac)₂] precursor. Catecholase-like activity of Cu(II) complexes via oxidation of 3,5-di-tert-butylcatechol (3,5-DTBC) to 3,5-di-tert-butylquinone (3,5-DTBQ) was performed. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Name: copper(ii)hexafluor-2,4-pentanedionate).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Copper has continued to be one of the most utilized and important transition metal catalysts in synthetic organic chemistry. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.Name: copper(ii)hexafluor-2,4-pentanedionate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Synthesis and reactions of N-heterocycle functionalised variants of heterometallic {Cr₇Ni} rings was written by Whitehead, George F. S.;Ferrando-Soria, Jesus;Carthy, Laura;Pritchard, Robin G.;Teat, Simon J.;Timco, Grigore A.;Winpenny, Richard E. P.. And the article was included in Dalton Transactions in 2016.Related Products of 14781-45-4 This article mentions the following:

Here the authors present a series of linked cage complexes of functionalized variants of the octametallic ring {Cr₇Ni} with the general formula [Pr₂NH₂][Cr₇NiF₈(O₂C^tBu)₁₅(O₂CR)], where HO₂CR is a N-heterocycle containing carboxylic acid. These compounds are made by reacting [Pr₂NH₂][Cr₇NiF₈(O₂C^tBu)₁₅(O₂CR)] with a variety of simple metal salts and metal dimers. The carboxylic acids studied include iso-nicotinic acid, 3-(4-pyridyl)acrylic acid and 4-pyridazine carboxylic acid. These new linked cage complexes have been studied structurally and the study highlights the versatility of functionalized {Cr₇Ni} as a Lewis base ligand. As {Cr₇Ni} is a putative mol. electron spin qubit this work contributes to the authors’ understanding of the chem. that might be required to assemble mol. spin qubits. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Related Products of 14781-45-4).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. The copper-mediated C-C, C-O, C-N, and C-S bond formation is a part of one oldest reaction, emphasizing the Ullmann cross-coupling reaction.Related Products of 14781-45-4

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper Mediated Intramolecular vs. Intermolecular Oxygenations: The Spacer makes the Difference! was written by Petrillo, Alexander;Hoffmann, Alexander;Becker, Jonathan;Herres-Pawlis, Sonja;Schindler, Siegfried. And the article was included in European Journal of Inorganic Chemistry in 2022.Synthetic Route of C2CuF6O6S2 This article mentions the following:

A copper(I) complex with an imine ligand derived from (+)-camphor and 2-(2-aminoethyl)pyridine that forms a bis(μ-hydroxido) dicopper complex upon reaction with dioxygen at room temperature It is detectable by UV-vis for several hours up to a few days, depending on the solvent and could be structurally characterized. In contrast to previous observations this complex rather oxygenates acetone or thioanisole as external substrates instead of undergoing an intramol. ligand hydroxylation. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Synthetic Route of C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, inexpensive and low toxicity. Copper nanoparticles can also catalyze the coupling reaction of nitrogen-containing nucleophiles, phenols, thiols, xanthogenates, selenium ruthenium nucleophiles and the like.Synthetic Route of C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Cu-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of N-Arylmaleimides: Access to Enantioenriched F₃C-Containing Octahydropyrrolo[3,4-c]pyrroles was written by Wang, Zhen-Hua;Liu, Ji-Hong;Zhang, Yan-Ping;Zhao, Jian-Qiang;You, Yong;Zhou, Ming-Qiang;Han, Wen-Yong;Yuan, Wei-Cheng. And the article was included in Organic Letters in 2022.HPLC of Formula: 34946-82-2 This article mentions the following:

With a Cu(OTf)₂/chiral ferrocenyl P,N-ligand complex as a catalyst, the enantioselective desymmetrization of N-arylmaleimides was successfully realized by taking advantage of the asym. 1,3-dipolar cycloaddition reaction of N-2,2,2-trifluoroethylisatin ketimines. A series of structurally diverse F₃C-containing octahydropyrrolo[3,4-c]pyrroles I [R¹ = H, 4-Br, 6-F, etc.; R² = Me, Et, allyl, Bn], bearing four contiguous carbon stereocenters and one stereogenic chiral C-N axial bond, were obtained with excellent results. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2HPLC of Formula: 34946-82-2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.HPLC of Formula: 34946-82-2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”