Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Name: Benzaldehyde Propylene Glycol Acetal, 2568-25-4, Name is Benzaldehyde Propylene Glycol Acetal, SMILES is CC1OC(C2=CC=CC=C2)OC1, belongs to copper-catalyst compound. In a document, author is Pacheco-Benichou, Alexandra, introduce the new discover.
Copper-Catalyzed C-H Arylation of Fused-Pyrimidinone Derivatives Using Diaryliodonium Salts
Copper-catalyzed Csp2-Csp2 bond forming reactions through C-H activation are still one of the most useful strategies for the diversification of heterocyclic moieties using various coupling partners. A catalytic protocol for the C-H (hetero)arylation of thiazolo[5,4-f]quinazolin-9(8H)-ones and more generally fused-pyrimidinones using catalyst loading of CuI with diaryliodonium triflates as aryl source under microwave irradiation has been disclosed. The selectivity of the transfer of the aryl group was also disclosed in the case of unsymmetrical diaryliodonium salts. Specific phenylation of valuable fused-pyrimidinones including quinazolinone are provided. This strategy enables a rapid access to an array of various (hetero)arylated N-containing polyheteroaromatics as new potential bioactive compounds.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 2568-25-4. Name: Benzaldehyde Propylene Glycol Acetal.
Reference:
Copper catalysis in organic synthesis – NCBI,
,Special Issue “Fundamentals and Applications of Copper-Based Catalysts”