So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Tercenio, Quentin D.; Alexanian, Erik J. researched the compound: (S)-2-Bromosuccinic acid( cas:20859-23-8 ).Application of 20859-23-8.They published the article 《Stereospecific Nickel-Catalyzed Reductive Cross-Coupling of Alkyl Tosylate and Allyl Alcohol Electrophiles》 about this compound( cas:20859-23-8 ) in Organic Letters. Keywords: alkyl tosylate allyl alc nickel reductive cross coupling allylation; allyl alkane preparation enantioselective. We’ll tell you more about this compound (cas:20859-23-8).
A nickel-catalyzed reductive coupling of allyl alcs. with chiral, nonracemic alkyl tosylates was reported. This cross-coupling delivered valuable allylation products with high levels of stereospecificity across a range of substrates. The catalytic system consisted of a simple nickel salt in conjunction with a com. available reductant and importantly represented a rare example of a cross-coupling involving the C-O bonds of two electrophiles.
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Reference:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”