Safety of Bis(acetylacetone)copperIn 2019 ,《Classes of non-conventional tetraspanins defined by alternative splicing》 was published in Scientific Reports. The article was written by Hochheimer, Nikolas; Sies, Ricarda; Aschenbrenner, Anna C.; Schneider, Dirk; Lang, Thorsten. The article contains the following contents:
Tetraspanins emerge as a family of membrane proteins mediating an exceptional broad diversity of functions. The naming refers to their four transmembrane segments, which define the tetraspanins’ typical membrane topol. In this study, we analyzed alternative splicing of tetraspanins. Besides isoforms with four transmembrane segments, most mRNA sequences are coding for isoforms with one, two or three transmembrane segments, representing structurally mono-, di- and trispanins. Moreover, alternative splicing may alter transmembrane topol., delete parts of the large extracellular loop, or generate alternative N- or C-termini. As a result, we define structure-based classes of non-conventional tetraspanins. The increase in gene products by alternative splicing is associated with an unexpected high structural variability of tetraspanins. We speculate that non-conventional tetraspanins have roles in regulating ER exit and modulating tetraspanin-enriched microdomain function.Bis(acetylacetone)copper(cas: 13395-16-9Safety of Bis(acetylacetone)copper) was used in this study.
Bis(acetylacetone)copper(cas: 13395-16-9) is used as PVC stabilizer, and curing agents for epoxy resins, acrylic adhesives and silicone rubbers. It is also used as solvents, lubricant additives, paint drier, and pesticides.Safety of Bis(acetylacetone)copper
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”