Copper oxidation chemistry using a 19-iminopyridine-bearing steroidal ligand: (i) C5-C6 olefin difunctionalization and (ii) C1β-hydroxylation/C19-peroxidation was written by Offei, Samuel D.;Arman, Hadi D.;Yoshimoto, Francis K.. And the article was included in Steroids in 2022.Reference of 34946-82-2 This article mentions the following:
In this study, a 19-imino pyridine DHEA derivative was synthesized and was treated with copper nitrate and hydrogen peroxide. Results showed the difunctionalization of an olefin for δ-5 steroid substrates to yield a 5-β-hydroxylated 6-α-nitrate ester product. In contrast, for 19-imino pyridine precursors with a 5-α-androstane steroid backbone, a 1-β-hydroxylation and 19-peroxidation occurred to yield a 1-β-hydroxylated 19-imidoperoxoic acid product I. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Reference of 34946-82-2).
Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. Copper catalyst has received great attention owing to the low toxicity and low cost. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Reference of 34946-82-2
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”