34946-82-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Copper(II) trifluoromethanesulfonate, cas is 34946-82-2,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.
2-Phenylpyridine 1a (71 muL, 0.5 mmol),1,2-diphenylethylene 2a (89.7 mg, 0.5 mmol),{[Cp * RhCl2] 2} (3.1 mg, 1 mol%),AgOTf (5.1 mg, 0.02 mmol),Cu (OTf) 2 (180.8 mg, 0.5 mmol)Was added to 2.0 mL of methanol, under argon (1 atm)120 oC reaction after 22 hours to stop the reaction,Diatomaceous earth filter, dichloromethane washing, collecting organic phase evaporated solvent,Methanol / ether / petroleum ether (1: 4: 100) to give the pure isoquinoline salt derivative 3aa. The product was a white solid in 91%
The chemical industry reduces the impact on the environment during synthesis,34946-82-2,Copper(II) trifluoromethanesulfonate,I believe this compound will play a more active role in future production and life.
Reference£º
Patent; Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences; Huang, Hanmin; Zhang, Guoyang; (21 pag.)CN104177357; (2017); B;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”