As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO179,mainly used in chemical industry, its synthesis route is as follows.,14172-91-9
The copper tetraphenyl porphyrinssynthesised as above was converted into itsoctabromo derivative by the addition of liquidbromine (1.2ml)in chloroform(50ml) to a solution ofCu(TPP)(0.50g) in chloroform:carbon tetrachloride(1:1 V/V) (500ml) in a conical flask. Bromine wasadded dropwise and slowly over a period of halfhour, at room temperature. The contents were stirredfor 4hours, followed by addition of pyridine 2.4mlin 40ml mixture of CHCl3:CCl4in 1:1 ratio. Theaddition took about half hour and stirring continuedfor 12hours. The bromination process wasmonitored by UV-visible spectroscopy to ensurecomplete bromination. The excess bromine was destroyed byaddition of sodium metasulphite (200ml 20% aq.solution) to the system. The organic layer wasseparated using a separating funnel and the solutionwas dried over anhydrous sodium sulphate. Theevaporation of solvent under reduced pressureresulted a green solid of copper octabromoteraphenylporphyrin [Cu(OBTPP)]. The solid was dissolved inminimum amount of chloroform and columnchromatography was done. The first fraction comingout of the column was collected. The removal of solventyielded copper octabromotetraphenyl porphyrin(3)in purified form, yield (75%).
With the complex challenges of chemical substances, we look forward to future research findings about 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),belong copper-catalyst compound
Reference£º
Article; Raikwar, Kalpana; Oriental Journal of Chemistry; vol. 31; 2; (2015); p. 1195 – 1200;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”