In an article, author is Treacy, Sean M., once mentioned the application of 2568-25-4, Category: copper-catalyst, Name is Benzaldehyde Propylene Glycol Acetal, molecular formula is C10H12O2, molecular weight is 164.2, MDL number is MFCD00059732, category is copper-catalyst. Now introduce a scientific discovery about this category.
Copper Catalyzed C(sp(3))- H Bond Alkylation via Photoinduced Ligand-to-Metal Charge Transfer
Utilizing catalytic CuCl2 we report the functionalization of numerous feedstock chemicals via the coupling of unactivated C(sp(3))-H bonds with electron-deficient olefins. The active cuprate catalyst undergoes Ligand-to-Metal Charge Transfer (LMCT) to enable the generation of a chlorine radical which acts as a powerful hydrogen atom transfer reagent capable of abstracting strong electron-rich C(sp(3))-H bonds. Of note is that the chlorocuprate catalyst is an exceedingly mild oxidant (0.5 V vs SCE) and that a proposed protodemetalation mechanism offers a broad scope of electron-deficient olefins, offering high diastereoselectivity in the case of endocyclic alkenes. The coupling of chlorine radical generation with Cu reduction through LMCT enables the generation of a highly active HAT reagent in an operationally simple and atom economical protocol.
If you are interested in 2568-25-4, you can contact me at any time and look forward to more communication. Category: copper-catalyst.
Reference:
Copper catalysis in organic synthesis – NCBI,
,Special Issue “Fundamentals and Applications of Copper-Based Catalysts”