Reference of (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride, is researched, Molecular C20H28ClN3O6, CAS is 89396-94-1, about Bioequivalence study of Imidapril hydrochloride tablets 10mg in healthy male volunteers: comparison of Imidapril hydrochloride tablets 10mg “”TCK”” and Imidapril hydrochloride tablets 10mg “”TYK”” with Tanatril tablets 10. Author is Tanaka, Kazuhiko.
To investigate the bioequivalence of Imidapril hydrochloride tablets 10 mg [TCK] and Imidapril hydrochloride tablets 10 mg [TYK] (test product) with Tanatril tablets 10 (reference product), these were administered to healthy male adult subjects in a two-way, two-period crossover study and their bioavailability were compared by the parameters of AUCt and Cmax determined from plasma concentrations of unchanged imidapril. Since the 90% confidence intervals of the differences between the means of the logarithmic AUCt and Cmax of the test and reference products were within the acceptable range specified in the “”Guideline for bioequivalence studies of generic products””, it was concluded that the two test products were equivalent to the reference one biol.
《Bioequivalence study of Imidapril hydrochloride tablets 10mg in healthy male volunteers: comparison of Imidapril hydrochloride tablets 10mg “”TCK”” and Imidapril hydrochloride tablets 10mg “”TYK”” with Tanatril tablets 10》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound((S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride)Reference of (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride.
Reference:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”