Category: copper-catalyst

An X-ray photoelectron spectroscopy and quantum chemical study of copper(II) β-diketonates and Cu(HFA)₂ complexes with imidazoline ligands was written by Kryuchkova, Natalya A.;Stabnikov, Pavel A.;Kalinkin, Alexander V.;Fursova, Elena Yu.. And the article was included in Journal of Electron Spectroscopy and Related Phenomena in 2016.Application In Synthesis of copper(ii)hexafluor-2,4-pentanedionate This article mentions the following:

An XPS study of the charge and spin state of copper(II) β-diketonates and Cu(hfa)₂ (hfa-hexafluoroacetylacetonate) complexes with imidazoline ligands is performed with comparison to the data of quantum chem. calculations It is shown that the structure of the spectra of copper is described by a superposition of the |2p⁵3d⁹> and | 2p⁵3d¹⁰L> electronic states determined by electron transfer processes between copper and L ligand atoms. It is found that during the coordination of imidazoline ligands to the Cu(hfa)₂ complex the spin d. is redistributed through the chain of chem. bonds from the ligand nitroxyl group to the copper atom. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Application In Synthesis of copper(ii)hexafluor-2,4-pentanedionate).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Copper catalyst has received great attention owing to the low toxicity and low cost. These ligands enable the reaction promoted in mild condition. The reaction scope has also been greatly expanded, rendering this copper-based cross-coupling attractive for both academia and industry. Application In Synthesis of copper(ii)hexafluor-2,4-pentanedionate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Slow Magnetic Relaxation Behavior in Rare Ln-Cu-Ln Linear Trinuclear Complexes was written by Zhang, Junqing;Li, Cun;Wang, Juanjuan;Zhu, Mei;Li, Licun. And the article was included in European Journal of Inorganic Chemistry in 2016.Category: copper-catalyst This article mentions the following:

Three novel heterotrinuclear complexes {[Ln(hfac)₃]₂CuL₂} [Ln^III = Gd (1), Tb (2), and Dy (3); HL = 4-methoxysalicylaldehyde, hfac = hexafluoroacetylacetonate] were synthesized and characterized by x-ray crystallog. as well as by a study of their magnetic properties. In these compounds, Cu^II and Ln^III ions are bridged by two phenolato and aldehyde O atoms from two 4-methoxysalicylaldehyde ligands and one O atom from one hfac ligand, resulting in a linear trinuclear core of Ln-Cu-Ln with one central Cu^II ion and two terminal Ln^III ions. Also, the linear trinuclear units generate a pseudo-one-dimensional chain through π-π interactions. Direct-current magnetic susceptibility studies show that there is a ferromagnetic interaction between Cu^II and Gd^III ions. Tb and Dy complexes exhibit frequency-dependent out-of-phase signals, indicating slow magnetic relaxation behavior. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Category: copper-catalyst).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Category: copper-catalyst

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Ligand-Enabled Copper-Catalyzed Regio- and Stereoselective Allylboration of 1-Trifluoromethylalkenes was written by Kojima, Yuki;Nishii, Yuji;Hirano, Koji. And the article was included in Organic Letters in 2022.Formula: C2CuF6O6S2 This article mentions the following:

A Cu-catalyzed regio- and stereoselective allylboration of 1-trifluoromethylalkenes with bis(pinacolato)diboron (pinB-Bpin) and allylic chlorides was developed to form functionalized trifluoromethylated products with high diastereoselectivity. The key to success is the judicious choice of Cs₂CO₃ base and t-Bu-modified dppe-type ligand, which enables the otherwise challenging high catalyst turnover and suppression of the competing defluorination side reaction from an alkylcopper intermediate. The product derivatization of the resulting Bpin moiety can deliver diverse CF₃-containing mols. with high stereochem. fidelity. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Formula: C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, inexpensive and low toxicity. The copper-mediated C-C, C-O, C-N, and C-S bond formation is a part of one oldest reaction, emphasizing the Ullmann cross-coupling reaction.Formula: C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Heterophasic synthesis of bimetallic In hexafluoroacetylacetonate complexes with transition metals was written by Zheleznova, L. I.;Slyusarchuk, L. I.;Trunova, E. K.. And the article was included in Ukrainskii Khimicheskii Zhurnal (Russian Edition) in 2016.SDS of cas: 14781-45-4 This article mentions the following:

Heterometallic hexafluoroacetylacetonate (hfacac) complexes [MIn(hfacac)₅] [M = Co(II), Cu(II), Zn] and [NdIn(hfacac)₆] were prepared and examined by IR and UV-vis. diffuse reflectance spectra. The method of synthesis of heteronuclear hexafluoroacetylacetonate complexes which is based on the interaction of the metallic indium dissolved in the hexafluoroacetylacetone and acetonitrile medium in the presence of the oxidizing agent (air oxygen) with an oxide or a chloride of transition metal is suggested. The synthesis of the complexes is carried out in the mild conditions without a use of aggressive reagents, high temperatures and special equipment. Novel heterometallic complexes with the composition of MIn(HFA)_n·AN_m (M – Co(II), Cu(II), Zn(II), Nd(III)) were synthesized. According to IR-spectroscopy, electronic absorption spectra and DTA, it was established that the coordination center of Co(II) and Cu(II) has the structure of distorted octahedron in the complexes with 3d-metals while the neodymium heterometallic complex has C_4v symmetry with coordination number 8 for Nd (III). Based on comparison of the thermal anal. for mono- and heteronuclear hexafluoroacetylacetonate it was shown that heterometallic complexes have a wide interval of stability in a gas phase and low sublimation temperatures In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4SDS of cas: 14781-45-4).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to the earth-abundant, low toxicity and inexpensive. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.SDS of cas: 14781-45-4

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Effective Preparation of [¹⁸F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor was written by Haskali, Mohammad B.;Roselt, Peter D.;O’Brien, Terence J.;Hutton, Craig A.;Ali, Idrish;Vivash, Lucy;Jupp, Bianca. And the article was included in Molecules in 2022.Formula: C2CuF6O6S2 This article mentions the following:

[¹⁸F]Flumazenil 1 ([¹⁸F]FMZ) is an established positron emission tomog. (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABAA in the brain. The production of [¹⁸F]FMZ 1 for its clin. use has proven to be challenging, requiring harsh radiochem. conditions, while affording low radiochem. yields. Fully characterized, new methods for the improved production of [¹⁸F]FMZ 1 are needed. We investigate the use of late-stage copper-mediated radiofluorination of aryl stannanes to improve the production of [¹⁸F]FMZ 1 that is suitable for clin. use. Mass spectrometry was used to identify the chem. byproducts that were produced under the reaction conditions. The radiosynthesis of [¹⁸F]FMZ 1 was fully automated using the iPhase FlexLab radiochem. module, affording a 22.2 ± 2.7% (n = 5) decay-corrected yield after 80 min. [18F]FMZ 1 was obtained with a high radiochem. purity (>98%) and molar activity (247.9 ± 25.9 GBq/μmol). The copper-mediated radiofluorination of the stannyl precursor is an effective strategy for the production of clin. suitable [18F]FMZ 1. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Formula: C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to low toxicity and inexpensive, earth-abundant. Copper of different valence states can be used to catalyze the coupling reaction, especially the Ullmann coupling reaction. Formula: C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Ph(i-PrO)SiH₂: An Exceptional Reductant for Metal-Catalyzed Hydrogen Atom Transfers was written by Obradors, Carla;Martinez, Ruben M.;Shenvi, Ryan A.. And the article was included in Journal of the American Chemical Society in 2016.Reference of 14781-45-4 This article mentions the following:

We report the discovery of an outstanding reductant for metal-catalyzed radical hydrofunctionalization reactions. Observations of unexpected silane solvolysis distributions in the HAT-initiated hydrogenation of alkenes reveal that phenylsilane is not the kinetically preferred reductant in many of these transformations. Instead, isopropoxy(phenyl)silane forms under the reaction conditions, suggesting that alcs. function as important silane ligands to promote the formation of metal hydrides. Study of its reactivity showed that isopropoxy(phenyl)silane is an exceptionally efficient stoichiometric reductant, and it is now possible to significantly decrease catalyst loadings, lower reaction temperatures, broaden functional group tolerance, and use diverse, aprotic solvents in iron- and manganese-catalyzed hydrofunctionalizations. As representative examples, we have improved the yields and rates of alkene reduction, hydration, hydroamination, and conjugate addition Discovery of this broadly applicable, chemoselective, and solvent-versatile reagent should allow an easier interface with existing radical reactions. Finally, isotope-labeling experiments rule out the alternative hypothesis of hydrogen atom transfer from a redox-active β-diketonate ligand in the HAT step. Instead, initial HAT from a metal hydride to directly generate a carbon-centered radical appears to be the most reasonable hypothesis. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Reference of 14781-45-4).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Reference of 14781-45-4

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Understanding the effect of structural changes on slow magnetic relaxation in mononuclear octahedral copper(II) complexes was written by Marcinkowski, Dawid;Adamski, Ariel;Kubicki, Maciej;Consiglio, Giuseppe;Patroniak, Violetta;Slusarski, Tomasz;Acikgoz, Muhammed;Szeliga, Daria;Vadra, Nahir;Karbowiak, Miroslaw;Stefaniuk, Ireneusz;Rudowicz, Czeslaw;Gorczynski, Adam;Korabik, Maria. And the article was included in Dalton Transactions in 2022.Quality Control of Copper(II) trifluoromethanesulfonate This article mentions the following:

Current advances in mol. magnetism are aimed at the construction of mol. nanomagnets and spin qubits for their use as high-d. data storage materials and quantum computers. Mononuclear coordination compounds with low spin values of S = 1/2 are excellent candidates for this endeavour, but knowledge of their construction via rational design is limited. This particularly applies to the single copper(II) spin center, having been only recently demonstrated to exhibit slow relaxation of magnetization in the appropriate octahedral environment. The authors thus prepared a unique organic scaffold that would allow one to gain in-depth insight into how purposeful structural differences affect the slow magnetic relaxation in monometallic, transition metal complexes. As a proof-of-principle, one can construct two, structurally very similar complexes with isolated Cu(II) ions in an octahedral ligand environment, the magnetic properties of which differ significantly. The differences in structural symmetry effects and in magnetic relaxation are corroborated with exptl. techniques and theor. approaches, showing how symmetry distortions and crystal packing affect the relaxation behavior in these isolated Cu(II) systems. The unique organic platform can be efficiently used for the construction of various transition-metal ion systems in the future, effectively providing a model system for investigation of magnetic relaxation via targeted structural distortions. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Quality Control of Copper(II) trifluoromethanesulfonate).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents has turned up as an exceedingly robust synthetic tool. It is clear from the impact copper catalysis has had on organic synthesis that copper should be considered a first line catalyst for many organic reactions.Quality Control of Copper(II) trifluoromethanesulfonate

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Synthesis and structural characterization of Mn(II) and Cu(II) complexes with bis(4-(1H-imidazol-1-yl)phenyl)methanone ligands was written by Wang, Gao-Feng;Zhang, Xiao;Liu, Zhao-Rong;Wang, Yu-Chun;Jiang, Hong-Shi;Li, Mei-Zhuan;Jiao, Jiao;Ma, Hui-Xuan;Jiang, Xiu-Ping;Han, Qiu-Ping. And the article was included in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences in 2017.Category: copper-catalyst This article mentions the following:

Two complexes, {Mn(hfac)₂(BIPMO)}_n (1), {Cu(hfac)₂(BIPMO)}_n (2) [hfac = 1,1,1,5,5,5-hexafluoro-pentane-2,4-dionato(-), BIPMO = bis(4-(1H-imidazol-1-yl)phenyl)methanone], with the V-shaped ligands were synthesized and characterized by IR spectroscopy, elemental analyses, along with single-crystal x-ray diffraction analyses. The x-ray diffraction studies have shown that the metal ions in 1 and 2 are both six-coordinated to two nitrogen atoms of two BIPMO ligands and four oxygen atoms of two hfac ligands to form a distorted octahedral geometry. Each BIPMO ligand acts as a bridging ligand to link two adjacent metal(II) atoms to form a helical chain in the crystal structure. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Category: copper-catalyst).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to low toxicity and inexpensive, earth-abundant. Copper nanoparticles can also catalyze the coupling reaction of phenols, thiols, xanthogenates, nitrogen-containing nucleophiles, selenium ruthenium nucleophiles and the like.Category: copper-catalyst

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Asymmetric Alkynylation of Tertiary Carbon-Centered Radical via Copper-Catalyzed Radical Relay was written by Wu, Dunqi;Wu, Lianqian;Chen, Pinhong;Liu, Guosheng. And the article was included in Chinese Journal of Chemistry in 2022.Application of 34946-82-2 This article mentions the following:

Alkynes are frequently found in a high proportion of natural products and bioactive moleculars, as well as a common synthon in organic synthesis, which can be easily transformed to an alkenyl, alkyl, heteroaryl, or carboxylic acid group. The enantioselective construction of alkyne substituted all carbon quaternary stereocenters is rarely reported and still a big challenge. As part of the continuous effort on developing asym. radical transformations, it was found that introducing an amidyl group (CONHAr) adjacent to the tertiary carbon radical could enable the asym. radical coupling with alkyne reagents. The amidyl group may stabilize the tertiary carbon radical or coordination with the chiral copper catalyst. Herein, a copper-catalyzed asym. trifluoromethyl-alkynylation of α-aryl substituted acrylamides, which provides a straightforward and efficient access to chiral quaternary all-carbon centers bearing alkynyl groups in good yields and enantioselectivities is reported. This reaction was also applied for the synthesis of chiral functionalized dipeptide. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Application of 34946-82-2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. Transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents belong to the most important cross-coupling reaction in organic synthesis. Copper nanoparticles can also catalyze the coupling reaction of phenols, thiols, xanthogenates, nitrogen-containing nucleophiles, selenium ruthenium nucleophiles and the like.Application of 34946-82-2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A New Nitronyl Nitroxide Radical as Building Blocks for a Rare S = 13/2 High Spin Ground State 2p-3d Complex and a 2p-3d-4f Chain was written by Yao, Binling;Guo, Zhilin;Zhang, Xuan;Ma, Yue;Yang, Zhenhao;Wang, Qinglun;Li, Licun;Cheng, Peng. And the article was included in Crystal Growth & Design in 2017.Formula: C10H2CuF12O4 This article mentions the following:

A new nitronyl nitroxide radical L (L = 2-(4-(5-methyl-carbonyl-3-pyriyl)benzoxo)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide) containing N-O groups and the pyridyl nitrogen group was designed and synthesized as a multidentate ligand to obtain compounds with interesting structures and magnetic properties from 3d or 3d-4f precursors. The reaction of Cu(hfac)₂ and/or Gd(hfac)₃·2H₂O (hfac = hexafluoroacetylacetonate) with L resulted in a rare S = 13/2 high spin ground state Cu^II complex [(Cu(hfac)₂)₇(L)₆] (1) and a Cu^II-Gd^III chain complex [Gd(hfac)₃Cu(hfac)₂(L)₂]_n·0.5CH₂Cl₂ (2). Single crystal X-ray diffraction studies indicate that the N-O groups of the L radicals are all axially bound to Cu^II ions in complex 1, which result in the ferromagnetic exchange between Cu^II and radicals and an S = 13/2 high spin ground state. While adding Gd(hfac)₃ units to the system of Cu(hfac)₂ and L radical, a one dimension chain structure is obtained, and there are ferromagnetic Gd^III-radical interactions and antiferromagnetic radical-radical coupling in the chain. In the experiment, the researchers used many compounds, for example, copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4Formula: C10H2CuF12O4).

copper(ii)hexafluor-2,4-pentanedionate (cas: 14781-45-4) belongs to copper catalysts. Copper has continued to be one of the most utilized and important transition metal catalysts in synthetic organic chemistry. Copper nanoparticles can also catalyze the coupling reaction of phenols, thiols, xanthogenates, nitrogen-containing nucleophiles, selenium ruthenium nucleophiles and the like.Formula: C10H2CuF12O4

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”