Category: copper-catalyst

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO149,mainly used in chemical industry, its synthesis route is as follows.,578743-87-0

In a glove box, IPrCuCl (224 mg, 0.46 mmol) and potassium tris(1-pyrazolyl)borohydride (127 mg, 0.50 mmol) in THF in a 40 mixture was stirred at room temperature for 3 hours dongan. Filtered through a plug of Celite and the reaction mixture after the evaporation of the solvent under reduced pressure to give product as a white powder IPrCuTp

With the complex challenges of chemical substances, we look forward to future research findings about [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,belong copper-catalyst compound

Reference£º
Patent; University Of Southern California; Thompson, Mark E; Hamz, Rasya; Durovitch, Peter I; (50 pag.)KR2015/26932; (2015); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO179,mainly used in chemical industry, its synthesis route is as follows.,14172-91-9

The copper tetraphenyl porphyrinssynthesised as above was converted into itsoctabromo derivative by the addition of liquidbromine (1.2ml)in chloroform(50ml) to a solution ofCu(TPP)(0.50g) in chloroform:carbon tetrachloride(1:1 V/V) (500ml) in a conical flask. Bromine wasadded dropwise and slowly over a period of halfhour, at room temperature. The contents were stirredfor 4hours, followed by addition of pyridine 2.4mlin 40ml mixture of CHCl3:CCl4in 1:1 ratio. Theaddition took about half hour and stirring continuedfor 12hours. The bromination process wasmonitored by UV-visible spectroscopy to ensurecomplete bromination. The excess bromine was destroyed byaddition of sodium metasulphite (200ml 20% aq.solution) to the system. The organic layer wasseparated using a separating funnel and the solutionwas dried over anhydrous sodium sulphate. Theevaporation of solvent under reduced pressureresulted a green solid of copper octabromoteraphenylporphyrin [Cu(OBTPP)]. The solid was dissolved inminimum amount of chloroform and columnchromatography was done. The first fraction comingout of the column was collected. The removal of solventyielded copper octabromotetraphenyl porphyrin(3)in purified form, yield (75%).

With the complex challenges of chemical substances, we look forward to future research findings about 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),belong copper-catalyst compound

Reference£º
Article; Raikwar, Kalpana; Oriental Journal of Chemistry; vol. 31; 2; (2015); p. 1195 – 1200;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

142-71-2, Copper(II) acetate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,142-71-2

To a 250 mL round bottom flask equipped with a reflux condenser was charged 1.000 g (1.6 mmol) of 5,10,15,20-tetraphenylporphyrin and 100 ml of N, N-dimethylformamide (DMF) , Heated to reflux (about 154 ), until it is completely dissolved,A solution of 650 g (3.2 mmol) of copper acetate in 50 mL of DMF was added thereto, followed by reaction at 150 C using thin layer chromatography (developing solvent in a 1: 1 by volume mixture of chloroform and petroleum ether) After about 0.5 hours of reaction, the raw material point disappears and the reaction is complete. The reaction solution is poured into 100 mL of ice water while hot, allowed to stand for 30 min and then filtered. The solid is washed with ethanol and washed to the filtrate. The crude product was dried in a vacuum. The product was 1.010 g, yield 93.5%.

The synthetic route of 142-71-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Wuhan Institute of Technology; Gao, Hong; Wang, Huidong; Chen, Chujun; Huang, Qihao; (17 pag.)CN106366086; (2017); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,578743-87-0

In a dry double-mouth bottle to place Ir – 1 (0.0695 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.064 g, and the yield is 50%.

As the paragraph descriping shows that 578743-87-0 is playing an increasingly important role.

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,578743-87-0

In a dry double-mouth bottle to place Pt – 3 (0.0594 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.047 g, and the yield is 40%.

578743-87-0 is used more and more widely, we look forward to future research findings about [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

142-71-2, Copper(II) acetate is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,142-71-2

Copper tetraphenyl porphyrin was synthesised by taking tetra phenyl porphyrin[H2(TPP)]16(500mg) in chloroform(100ml).Copper(II) acetate(200mg) in glacial aceticacid(50ml) was added to the above solution andthe mixture was refluxed for 2hrs. The contents wereconcentrated to a volume of about 50-60ml andcooled to room temperature which resulted in crudecopper-tetraphenyl porphyrin Cu(TPP) (about450mg). The crude product was purified by columnchromatography using neutral alumina andchloroform as eluent. On elution the unreactedtetraphenyl porphyrin was eluted out first, followedby pure Cu(TPP). The chloroform fraction containingCu(TPP) was concentrated to obtain pure crystalsof Cu(TPP)[2]. The formation of Cu(TPP) wasmonitored by UV-visible spectroscopy which givepeaks-around 580, 541 and 417nm respectivelyconfirming the formation of Cu(TPP) (yield=400mg).

142-71-2 Copper(II) acetate 8895, acopper-catalyst compound, is more and more widely used in various.

Reference£º
Article; Raikwar, Kalpana; Oriental Journal of Chemistry; vol. 31; 2; (2015); p. 1195 – 1200;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 578743-87-0, its synthesis route is as follows.,578743-87-0

General procedure: To a stirred solution of imidazolium salts (0.045 mmol), NaOtBu (4.3 mg, 0.045 mmol) and CuCl (4.5mg, 0.045 mmol) was added THF (0.5 mL, 0.09 M) at 30 oC under argon atmosphere. After stirring for 2 h, the solution of K+[CF3B(OMe)3]- (63.5 mg, 0.3 mmol, 6.0 equiv) in DMF (0.5 mL) was added dropwise. Then the mixture was kept stirring at 30 oC for 10 h. After that, the reaction was quenched with water. Aqueous layer was extracted with EtOAc (15 mL x 3), and the combined organic layers was washed with brine, dried over Na2SO4 and concentrated under reduced pressure. Then the crude product was purified by column chromatography on silica gel to give the imidazolinone 3b-d.

With the complex challenges of chemical substances, we look forward to future research findings about [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride

Reference£º
Article; Zeng, Wei; Wang, Enyu; Qiu, Rui; Sohail, Muhammad; Wu, Shaoxiang; Chen, Fu-Xue; Journal of Organometallic Chemistry; vol. 743; (2013); p. 44 – 48;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II), as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 14172-91-9, its synthesis route is as follows.,14172-91-9

Weigh 5,10,15,20-tetraphenyl copper porphyrin 1.000 g (1.5 mmol) was dissolved in a three-necked flask containing 175 mL of chloroform and dissolved by electromagnetic stirring at 40 C,Then add 15 mL of acetic acid,40 mL of acetic anhydride, followed by addition of .28 g (1.5 mmol) of copper nitrate, the reaction was carried out for about 25 min. Thin layer chromatography was carried out until the feed point was almost disappeared, poured into 200 mL of ice water mixture, neutralized with sodium hydroxide solution to pH = 9, and then washed several times, dried with anhydrous sodium sulfate, standing for one hour, pumping, the filtrate was concentrated to saturation, add 30mL hot methanol recrystallization.The solid was washed with methanol to a colorless, dry, bright purple crystal, beta-nitro-5,10,15,20-tetraphenyl copper porphyrin 0.90 g, yield 84%.

With the complex challenges of chemical substances, we look forward to future research findings about 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II)

Reference£º
Patent; Wuhan Institute of Technology; Gao, Hong; Wang, Huidong; Chen, Chujun; Huang, Qihao; (17 pag.)CN106366086; (2017); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is Bis(acetylacetone)copper, and cas is 13395-16-9, its synthesis route is as follows.,13395-16-9

General procedure: The monodisperse CuPd alloy NPs with composition controlwere synthesized by using a modified version of our estab-lished recipe for the CoPd alloy NPs [14]. In a typical synthesis of Cu75Pd25NPs, copper(II) acetylacetonate (0.35 mmol, 90 mg)and palladium(II) acetylacetonate (0.1 mmol, 31 mg) were dis-solved in 3 mL of OAm in a 10 mL of glass vial. In a four-necked glass reactor that allows to study under inert atmosphere,200 mg of MB was dissolved in 3 mL of OAm and 7 mL of 1-octadecene at 80C under magnetic stirring. Next, the metal precursor mixture was quickly injected into the reactor under argon environment. The reaction was then proceed for 1 h before cooled down to room temperature. Then, the colloidal NPs mixture was transferred into two separate centrifuge tubeand acetone/ethanol (v/v = 7/3) was added into the tubes. TheNP product was separated by centrifugation at 8500 rpm for10 min.

With the complex challenges of chemical substances, we look forward to future research findings about Bis(acetylacetone)copper

Reference£º
Article; Guengoermez, Kuebra; Metin, Oender; Applied Catalysis A: General; vol. 494; (2015); p. 22 – 28;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14172-91-9,5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),as a common compound, the synthetic route is as follows.,14172-91-9

(a) N-Bromosuccinimide (0.0131 g, 0.0737 mmol) was added with stirring to a solution of 0.02 g (0.0296 mol) of complex 5 in 10 mL of chloroform and the reaction mixture was heated under reflux for 5 min. The mixture was cooled, water was added, the organic layer was separated, washed with water, dried with Na2SO4, concentrated, chromatographed on aluminum oxide (using hexane, chloroform-hexane 1 : 2, and then chloroform as eluent), and reprecipitated from ethanol. Yield 0.016 g (0.0212 mmol), 72%. (b) N-Bromosuccinimide (0.00788 g, 0.0444 mmol) was added with stirring to a solution of 0.02 g (0.0296 mmol) of complex 5 in a mixture of 10 mL of chloroform and 1 mL of DMF, the reaction mixture was kept at ambient temperature for 35 min. The mixture was treated similarly to method a. Yield 0.017 g (0.0225 mmol), 76%. (c) A mixture of 0.02 g (0.0288 mmol) of porphyrin 2 and 0.052 g (0.288 mmol) of Cu(OAc)2 was dissolved in 10 mL of DMF, the reaction mixture was heated to reflux, cooled, poured into water, solid NaCl was added, the precipitate was separated by filtration, washed with water, dried, and chromatographed on aluminum oxide using chloroform as an eluent. Yield 0.02 g (0.0265 mmol), 85%. MS (m/z (Irel, %)): 754 (56) [M]+; for C44H27N4BrCu calcd.: 755. IR (nu, cm-1): 2926 s, 2855 m nu(C-H, Ph), 1790 w, 1680 w, 1488 s nu(C=C, Ph), 1457 m nu(C=N), 1366 m, 1345 s nu(C-N), 1193 s, 1169 w, 1146 m, 1072 m delta(C-H, Ph), 1005 s nu(C-C), 861 s, 796 s gamma(C-H, pyrrole ring), 749 s, 702 s, 689 m gamma(C-H, Ph). For C44H27N4BrCu anal. calcd. (%): C, 69.98; N,7.42; H, 3.60; Br, 10.58. Found (%): C, 69.72; N, 7.30; H, 3.65; Br 9.67.

As the paragraph descriping shows that 14172-91-9 is playing an increasingly important role.

Reference£º
Article; Chizhova; Shinkarenko; Zav?yalov; Mamardashvili, N. Zh.; Russian Journal of Inorganic Chemistry; vol. 63; 6; (2018); p. 732 – 735; Zh. Neorg. Khim.; vol. 63; 6; (2018); p. 695 – 699,5;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”