Category: copper-catalyst

[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.,578743-87-0

In a glovebox, a 30 mL round-bottom flask was charged with (IPr)CuCl (969.0 mg, 2.00 mmol) and NaOtBu (192.0 mg, 2.00 mmol). Anhydrous THF (12.0 mL) was added. The resulting opaque brown solution was stirred for 2.0 h. It was filtered through Celite in glovebox and concentrated in vacuo affording (IPr)Cu(OtBu) as an off-white powder (802.2 mg, 79% yield).

With the rapid development of chemical substances, we look forward to future research findings about [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride

Reference£º
Article; Zeng, Wei; Wang, Enyu; Qiu, Rui; Sohail, Muhammad; Wu, Shaoxiang; Chen, Fu-Xue; Journal of Organometallic Chemistry; vol. 743; (2013); p. 44 – 48;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(II) acetate, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 142-71-2, its synthesis route is as follows.,142-71-2

General procedure: The reactions of complexing between porphyrins and copper acetate were studied by means of spectrophotometry in the range of 293-318 K. The change in temperature during the experiment did not exceed¡À0.1 K.

With the complex challenges of chemical substances, we look forward to future research findings about Copper(II) acetate

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Article; Pukhovskaya; Nam, Dao Tkhe; Fien, Chan Ding; Domanina; Ivanova, Yu. B.; Semeikin; Russian Journal of Physical Chemistry; vol. 91; 9; (2017); p. 1692 – 1702; Zh. Fiz. Khim.; vol. 91; 9; (2017); p. 1508 – 1519,12;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Copper(I) oxide, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 1317-39-1, its synthesis route is as follows.,1317-39-1

3-Chloro-4-nitro-benzonitrile Sodium nitrite (6.78 g in water (40 mL) at 0 C.) was slowly added to a solution of 4-amino-3-chloro-benzonitrile (10.5 g) in water (30 mL) and concentrated hydrochloric acid (30 mL) also at 0 C. After 10 minutes the solution was poured onto a suspension of cuprous oxide (3.48 g) and sodium nitrite (31.69 g) in water (100 mL) at 0 C. The ensuing mixture was stirred at 0 C. for 1 hour then at 23 C. for 1 hour. The resulting mixture was extracted with dichloromethane and the organic layer washed with saturated sodium chloride. The separated organic layer was dried over sodium sulfate and then concentrated to give 3-chloro-4-nitro-benzonitrile (11.31 g).

With the complex challenges of chemical substances, we look forward to future research findings about Copper(I) oxide

Reference£º
Patent; Pfizer Inc.; US2003/78432; (2003); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Bis(acetylacetone)copper, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 13395-16-9, its synthesis route is as follows.,13395-16-9

Cu(C5H7O2)2 (13.1 mg, 0.05 mmol) was solubilized in 5 mL of methanoland added to a 5 mL of methanolic solution of HL (24.0 mg,0.1 mmol). The mixture was stirred under reflux for 1 h. Dark greencrystals suitable for X-ray diffraction analysis were obtained after somedays from the mother liquor at room temperature. Yield: 22.9 mg(84.5%). Melting point: Decomposes after 260 C. Molar conductivity(1 mM, DMF): 0.35 Omega-1¡¤cm2¡¤mol-1 Elemental analysis calculated forC26H22O2N8Cu (%): C. 57.61; H. 4.09; N. 20.67. Found (%): C. 57.65; H.3.83; N. 20.64. IR bands (KBr, cm-1): nu(CeO) 1371; nu(C]N) 1580,1557; nu(NeN) 1160; rho(py) 735. ESI-MS [C26H23O2N8Cu]+ calcd./found(m/z)=542.1240, 542.1251.

With the complex challenges of chemical substances, we look forward to future research findings about Bis(acetylacetone)copper

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Article; Santiago, Pedro H.O.; Santiago, Mariana B.; Martins, Carlos H.G.; Gatto, Claudia C.; Inorganica Chimica Acta; vol. 508; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is Bis(acetylacetone)copper, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 13395-16-9, its synthesis route is as follows.,13395-16-9

General procedure: In a typical synthesis of Cu40Ag60, 0.45mmol Cu(acac)2 and 0.35 Ag (ac) was mixed with 3mL of OAm, 1 mL of OAc and 11mL of ODE. All synthesis was conducted in a four-necked glass reactor allowing the precise temperature control and inert gas atmosphere under dark conditions. Firstly, the mixture was heated to 60C and kept at this temperature for 10min. Then, the mixture was heated to 180C and kept at this temperature for 30min before it was cooled down to room temperature. After cooling, the resultant reaction mixture was collected with hexane (2mL) and the NPs were separated by centrifugation (8500rpm, 12min) after adding isopropanol (40mL). To further purify the yielded CuAg NPs, the product was centrifuged (8500rpm, 12min) one more time with ethanol (40mL). Finally, the remaining product was dispersed in hexane (10mL) for further use. By using the same recipe and varying metal precursor amounts, two different compositions of CuAg NPs were synthesized. Reductive mixing of 0.3mmol Cu(acac)2 and 0.5 Ag(ac) resulted in Cu30Ag70 NPs and mixing 0.6mmol Cu(acac)2 with 0.4 Ag (ac) led to Cu60Ag40. Synthesis of Ag NPs was conducted with the same recipe without using Cu precursor.

With the complex challenges of chemical substances, we look forward to future research findings about Bis(acetylacetone)copper

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Article; Balkan, Timucin; Kuecuekkececi, Hueseyin; Kaya, Sarp; Metin, Oender; Zarenezhad, Hamaneh; Journal of Alloys and Compounds; vol. 831; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belong copper-catalyst compound,Cuprouschloride,7758-89-6,Molecular formula: ClCu,mainly used in chemical industry, its synthesis route is as follows.,7758-89-6

EXAMPLE 1 N2-(4-Bromophenyl)-5-trifluoromethyl-1,3-benzoxazol-2-amine 4-Bromophenyl isothiocyanate (1.667 g, 7.785 mmol) was added to a solution of 2-amino-4-trifluoromethylphenol (1.379 g, 7.785 mmol) in tetrahydrofuran (THF) (100 mL) and the reaction was stirred at room temperature for about 16 hours then at about 50 C. for about another 5 hours. Copper (I) chloride (0.771 g, 7.785 mmol) and triethylamine (1.08 mL, 7.785 mmol) were added, and the mixture was stirred at room temperature for about 72 hours and then at about 50 C. for about another 18 hours. Additional copper (I) chloride (0.385 g) was added and the reaction was stirred at about 60 C. for about another 2 hours. The reaction was concentrated under reduced pressure, dissolved in methanol (200 mL), filtered through a pad of diatomaceous earth and the solvent removed in vacuo to afford N2-(4-bromophenyl)-5-trifluoromethyl-1,3-benzoxazol-2-amine as a brown solid (3.90 g, 140% of theory); RP-HPLC Rt 17.627 min, 77% purity (5% to 85% acetonitrile/0.1 M aqueous ammonium acetate, buffered to pH 4.5, over 20 min at 1 mL/min; lambda=254 nm; Waters Deltapak C18, 300 A, 5 mum, 150*3.9 mm column); and m/z 354.9 and 356.9 (M-H)-.

With the synthetic route has been constantly updated, we look forward to future research findings about Cuprouschloride,belong copper-catalyst compound

Reference£º
Patent; Wishart, Neil; Ritter, Kurt; US2003/9034; (2003); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO23,mainly used in chemical industry, its synthesis route is as follows.,7758-99-8

Using a 50 mL volumetric flask, 1.208 g of copper sulfate as a metal salt was dissolved in 50 mL of distilled water to prepare a 0.1 mol / L CuSO 4 aqueous solution. Next, 0.02 g (3.3 ¡Á 10 -5 mol) of tetraphenylporphyrin (TPP) as a compound having a porphyrin-type skeleton, 0.02 g (3.3 ¡Á 10 -5 mol) of copper sulfate Aqueous solution of sodium carbonate and 0.032 g of sodium carbonate equivalent to copper sulfate to prevent corrosion of the reaction vessel, and the interior of the reaction vessel was purged with argon and sealed. Next, the reaction vessel was charged into the sand bath set at 350 C. The reaction temperature in the reaction vessel reached the reaction temperature in about 4 minutes.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) sulfate pentahydrate,belong copper-catalyst compound

Reference£º
Patent; UTSUNOMIYA UNIVERSITY; SATO, TAKAFUMI; ITOH, NAOTSUGU; ITO, SATOSHI; (22 pag.)JP5823988; (2015); B2;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belong copper-catalyst compound,Copper(II) stearate,660-60-6,Molecular formula: C36H70CuO4,mainly used in chemical industry, its synthesis route is as follows.,660-60-6

General procedure: To a screw-cap reaction tube was added symmetrical N,N?-disubstituted guanidines 1a (0.2 mmol), PdCl2 (5 mol%, 1.8 mg), CuX2 (0.44 mmol). The reaction tube was evacuated and back-filled with CO (three times, balloon). PhCN (2 mL) was added using a syringe and the mixture was heated to the desired temperature with use of an oil bath. When the reaction was completed (detected by TLC), the mixture was cooled to room temperature and vented to discharge the excess CO. After the reaction was completed, the solvent was concentrated by evaporation in vacuo. The residue was purified by flash column chromatography on silica gel to afford the desired product Amides 6a with petroleum ether/ethyl acetate as the eluent.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) stearate,belong copper-catalyst compound

Reference£º
Article; Chang, Denghu; Zhu, Dan; Zou, Peng; Shi, Lei; Tetrahedron; vol. 71; 11; (2015); p. 1684 – 1693;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belong copper-catalyst compound,Copper(II) acetate,142-71-2,Molecular formula: C4H6CuO4,mainly used in chemical industry, its synthesis route is as follows.,142-71-2

Copper tetraphenyl porphyrin was synthesised by taking tetra phenyl porphyrin[H2(TPP)]16(500mg) in chloroform(100ml).Copper(II) acetate(200mg) in glacial aceticacid(50ml) was added to the above solution andthe mixture was refluxed for 2hrs. The contents wereconcentrated to a volume of about 50-60ml andcooled to room temperature which resulted in crudecopper-tetraphenyl porphyrin Cu(TPP) (about450mg). The crude product was purified by columnchromatography using neutral alumina andchloroform as eluent. On elution the unreactedtetraphenyl porphyrin was eluted out first, followedby pure Cu(TPP). The chloroform fraction containingCu(TPP) was concentrated to obtain pure crystalsof Cu(TPP)[2]. The formation of Cu(TPP) wasmonitored by UV-visible spectroscopy which givepeaks-around 580, 541 and 417nm respectivelyconfirming the formation of Cu(TPP) (yield=400mg).

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) acetate,belong copper-catalyst compound

Reference£º
Article; Raikwar, Kalpana; Oriental Journal of Chemistry; vol. 31; 2; (2015); p. 1195 – 1200;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belong copper-catalyst compound,Copper(II) acetate,142-71-2,Molecular formula: C4H6CuO4,mainly used in chemical industry, its synthesis route is as follows.,142-71-2

To a 250 mL round bottom flask equipped with a reflux condenser was charged 1.000 g (1.6 mmol) of 5,10,15,20-tetraphenylporphyrin and 100 ml of N, N-dimethylformamide (DMF) , Heated to reflux (about 154 ), until it is completely dissolved,A solution of 650 g (3.2 mmol) of copper acetate in 50 mL of DMF was added thereto, followed by reaction at 150 C using thin layer chromatography (developing solvent in a 1: 1 by volume mixture of chloroform and petroleum ether) After about 0.5 hours of reaction, the raw material point disappears and the reaction is complete. The reaction solution is poured into 100 mL of ice water while hot, allowed to stand for 30 min and then filtered. The solid is washed with ethanol and washed to the filtrate. The crude product was dried in a vacuum. The product was 1.010 g, yield 93.5%.

With the synthetic route has been constantly updated, we look forward to future research findings about Copper(II) acetate,belong copper-catalyst compound

Reference£º
Patent; Wuhan Institute of Technology; Gao, Hong; Wang, Huidong; Chen, Chujun; Huang, Qihao; (17 pag.)CN106366086; (2017); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”