Category: copper-catalyst

14172-91-9, 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II) is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a solution of corresponding porphyrin, the copper complex(1.13 mmol) in methylene chloride (90 mL) Cu(NO3)2¡¤3H2O(2.30 mmol) in the mixture of acetic acid (5 mL) and acetic anhydride (2 mL) was added, and reaction mixture was stirred for 3 h at room temperature, with TLC monitoring (CHCl3-hexane 1:2). After completion of the reaction the solution was washed with water (200 mL), then with Na2CO3 solution, and the organic phase was separated and dried over Na2SO4. After removal of the solvent under reduced pressure, the residue was purified by column chromatography on silica gel using a CH2Cl2-hexane system (3:7).

14172-91-9 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II) 3722750, acopper-catalyst compound, is more and more widely used in various.

Reference£º
Article; Ol’shevskaya, Valentina A.; Alpatova, Viktoriya M.; Radchenko, Alexandra S.; Ramonova, Alla A.; Petrova, Albina S.; Tatarskiy, Victor V.; Zaitsev, Andrei V.; Kononova, Elena G.; Ikonnikov, Nikolay S.; Kostyukov, Alexey A.; Egorov, Anton E.; Moisenovich, Mikhail M.; Kuzmin, Vladimir A.; Bragina, Natalya A.; Shtil, Alexander A.; Dyes and Pigments; vol. 171; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Bis(acetylacetone)copper, cas is 13395-16-9, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.

Under a nitrogen atmosphere, copper acetylacetonate (0.9 mmol) was dissolved in 25 mL of dichloromethane, followed by addition of 1,10-phenanthroline (0.9 mmol). The reaction solution was stirred at room temperature for 48 hours and then concentrated in vacuo. The resulting solid was washed with 25 mL of n-pentane and recrystallized with dichloromethane and n-pentane to obtain Catalyst 3. The method of the invention produces this compound in a yield of up to 75%

13395-16-9 is used more and more widely, we look forward to future research findings about Bis(acetylacetone)copper

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Patent; Chinese Academy Of Sciences Lanzhou Chemical Physics Institute Suzhou Institute; Li Yuehui; Wang Hua; Dong Yanan; Ke Lisitian¡¤shanduofu; (20 pag.)CN108017557; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Copper(II) sulfate pentahydrate, cas is 7758-99-8, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.

Example 2828.1 28.2[0329] Methyl 4-bromo-3-(trifluoromethoxy)benzoate (28.2). To a solution of 4-amino-3-(trifluoromethoxy)benzoic acid (2.00 g, 9.10 mmol) in MeOH (25.0 mL), was slowly added HCl (1.0 mL, 1.0 M in ether) at room temperature. The resulting reaction mixture was stirred at room temperature overnight. Benzene (20 mL) was added, and the reaction was heated at reflux with a Dean-Stark trap to remove the half volume of the solvent. The rest of the solvent was then evaporated to give the product. MS (ESI) m/e = 235.9 [M+l]+, Calc’d for CgHeF3NOs, 235.1. The crude product was used in the next step without further purification. To an ice-cooled suspension of methyl 4-amino-3- (trifluoromethoxy)benzoate hydrogen chloride salt (8.60 g, 31.70 mmol) in 17.1 mL of water and concentrated HBr (48 %, 17.1 mL), was slowly added a prepared 2.5 M solution of sodium nitrite (2.20 g in 12.7 mL) at 00C. The reaction mixture was stirred at 0 0C for 10 minutes. Meanwhile, a solution OfCuSO4 (6.68 g) in 35 mL of water was heated and sodium bromide (6.52 g) was added. The solution became a green color, and a solution OfNa2SOs (2.80 g) in water (10 mL) was then added to it. The solution was cooled at 0 0C and washed with water (25 x 3 mL). The water was then decanted off. Concentrated HBr (16.7 mL) was added, and the solution became a purple color. The solution of CuBr was slowly added to the diazonium salt (prepared above) at 00C. After addition, the ice-bath was removed, and an oil-bath was placed under the reaction vessel. The reaction mixture was then heated to 600C for 15 minutes, at 80 0C for 15 minutes, and then at 1000C for 20 minutes. The reaction mixture was next cooled to room temperature and made basic with Na2CO3 to a pH 8. The aqueous solution was extracted with EtOAc (100 x 2 mL). The organic layer was washed with brine (25 mL) and dried with MgSO4. The solvent was removed to give the crude product 28.2. 1H NMR (CDCl3) delta 3.96 (s, 3H), 7.75 (d, J= 8.4 Hz5 1 H), 7.86 (d, J= 8.4 Hz, 1 H), 7.98 (s, IH).

7758-99-8 is used more and more widely, we look forward to future research findings about Copper(II) sulfate pentahydrate

Reference£º
Patent; AMGEN INC.; WO2008/30520; (2008); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Bis(acetylacetone)copper, cas is 13395-16-9, it is a common heterocyclic compound, the copper-catalyst compound, its synthesis route is as follows.

General procedure: In a typical synthesis of Cu40Ag60, 0.45mmol Cu(acac)2 and 0.35 Ag (ac) was mixed with 3mL of OAm, 1 mL of OAc and 11mL of ODE. All synthesis was conducted in a four-necked glass reactor allowing the precise temperature control and inert gas atmosphere under dark conditions. Firstly, the mixture was heated to 60C and kept at this temperature for 10min. Then, the mixture was heated to 180C and kept at this temperature for 30min before it was cooled down to room temperature. After cooling, the resultant reaction mixture was collected with hexane (2mL) and the NPs were separated by centrifugation (8500rpm, 12min) after adding isopropanol (40mL). To further purify the yielded CuAg NPs, the product was centrifuged (8500rpm, 12min) one more time with ethanol (40mL). Finally, the remaining product was dispersed in hexane (10mL) for further use. By using the same recipe and varying metal precursor amounts, two different compositions of CuAg NPs were synthesized. Reductive mixing of 0.3mmol Cu(acac)2 and 0.5 Ag(ac) resulted in Cu30Ag70 NPs and mixing 0.6mmol Cu(acac)2 with 0.4 Ag (ac) led to Cu60Ag40. Synthesis of Ag NPs was conducted with the same recipe without using Cu precursor.

13395-16-9 is used more and more widely, we look forward to future research findings about Bis(acetylacetone)copper

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Article; Balkan, Timucin; Kuecuekkececi, Hueseyin; Kaya, Sarp; Metin, Oender; Zarenezhad, Hamaneh; Journal of Alloys and Compounds; vol. 831; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Bis(acetylacetone)copper,cas is 13395-16-9, mainly used in chemical industry, its synthesis route is as follows.

General procedure: CZTS nanoparticles were synthesized at different temperatures(220-320 C) for 3 hours and for variousreaction times (2-5 hours) at 240 C, usinghigh-temperature arrested precipitation in the coordinatingsolvent, oleylamine (OLA).15 Under the reactiontime of 3 hours, the reactants for synthesis ofCZTS nanoparticles didn?t dissolve enough in OLA.

As the rapid development of chemical substances, we look forward to future research findings about 13395-16-9

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Article; Kim, Donguk; Kim, Minha; Shim, Joongpyo; Kim, Doyoung; Choi, Wonseok; Park, Yong Seob; Choi, Youngkwan; Lee, Jaehyeong; Journal of Nanoscience and Nanotechnology; vol. 16; 5; (2016); p. 5082 – 5086;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Bis(acetylacetone)copper,cas is 13395-16-9, mainly used in chemical industry, its synthesis route is as follows.

The monodisperse CuPd alloy NPs with composition controlwere synthesized by using a modified version of our estab-lished recipe for the CoPd alloy NPs [14]. In a typical synthesis of Cu75Pd25NPs, copper(II) acetylacetonate (0.35 mmol, 90 mg)and palladium(II) acetylacetonate (0.1 mmol, 31 mg) were dis-solved in 3 mL of OAm in a 10 mL of glass vial. In a four-necked glass reactor that allows to study under inert atmosphere,200 mg of MB was dissolved in 3 mL of OAm and 7 mL of 1-octadecene at 80C under magnetic stirring. Next, the metal precursor mixture was quickly injected into the reactor under argon environment. The reaction was then proceed for 1 h before cooled down to room temperature. Then, the colloidal NPs mixture was transferred into two separate centrifuge tubeand acetone/ethanol (v/v = 7/3) was added into the tubes. TheNP product was separated by centrifugation at 8500 rpm for10 min.

As the rapid development of chemical substances, we look forward to future research findings about 13395-16-9

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Article; Guengoermez, Kuebra; Metin, Oender; Applied Catalysis A: General; vol. 494; (2015); p. 22 – 28;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is Bis(acetylacetone)copper,cas is 13395-16-9, mainly used in chemical industry, its synthesis route is as follows.

General procedure: In a typical synthesis of Cu40Ag60, 0.45mmol Cu(acac)2 and 0.35 Ag (ac) was mixed with 3mL of OAm, 1 mL of OAc and 11mL of ODE. All synthesis was conducted in a four-necked glass reactor allowing the precise temperature control and inert gas atmosphere under dark conditions. Firstly, the mixture was heated to 60C and kept at this temperature for 10min. Then, the mixture was heated to 180C and kept at this temperature for 30min before it was cooled down to room temperature. After cooling, the resultant reaction mixture was collected with hexane (2mL) and the NPs were separated by centrifugation (8500rpm, 12min) after adding isopropanol (40mL). To further purify the yielded CuAg NPs, the product was centrifuged (8500rpm, 12min) one more time with ethanol (40mL). Finally, the remaining product was dispersed in hexane (10mL) for further use. By using the same recipe and varying metal precursor amounts, two different compositions of CuAg NPs were synthesized. Reductive mixing of 0.3mmol Cu(acac)2 and 0.5 Ag(ac) resulted in Cu30Ag70 NPs and mixing 0.6mmol Cu(acac)2 with 0.4 Ag (ac) led to Cu60Ag40. Synthesis of Ag NPs was conducted with the same recipe without using Cu precursor.

As the rapid development of chemical substances, we look forward to future research findings about 13395-16-9

Reference£º
Article; Balkan, Timucin; Kuecuekkececi, Hueseyin; Kaya, Sarp; Metin, Oender; Zarenezhad, Hamaneh; Journal of Alloys and Compounds; vol. 831; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

A common heterocyclic compound, the copper-catalyst compound, name is 5,10,15,20-Tetraphenyl-21H,23H-porphine copper(II),cas is 14172-91-9, mainly used in chemical industry, its synthesis route is as follows.

To a stirred solution of (meso-tetraphenylporphyrinato)copper(II) (1c; 237 mg, 0.35 mmol) inCHCl3 (530 mL) at room temperature, a solution of 25% aqueous nitric acid (freshly prepared fromfuming yellow HNO3, d = 1.52; large excess, 140 mL, 637 mmol) was added dropwise during ca5 min. The reaction mixture was intensively stirred under argon in a round-bottomed ask, protectedagainst light, for 30-40 min with TLC monitoring (CHCl3/n-hexane-1:1). Then, the mixture waspoured into aqueous solution of 5% NaHCO3 (200 mL), and shaken carefully in a separatory funnel.The separated organic layer was washed with water (4 200 mL), and dried with anhydrousMgSO4/Na2CO3. After evaporating the solvent, the residue was subjected to column chromatography(eluent: CHCl3/n-hexane1:1) to give (2-nitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (2c; 71 mg, 28%) and a mixture of dinitro-substituted isomers (150 mg, 56%). Thedinitro-isomers were separated on preparative TLC (CHCl3/n-hexane-1:1, four times developed),allowing isolation of: (a) (2,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3ca; 40 mg,15%); (b) (3,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3cb; 35.5 mg, 13%); (c)(2,8-dinitro-5,10,15,20-tetra-phenylporphyrinato)copper(II) (3cc) contaminated with small amountsof (3,7-dinitro-5,10,15,20-tetraphenylporphyrinato)copper(II) (3cb) (30 mg, yield-ca 10%). 3cc can befurther purified by preparative TLC.

As the rapid development of chemical substances, we look forward to future research findings about 14172-91-9

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Article; Mikus, Agnieszka; Rosa, Mariusz; Ostrowski, Stanis?aw; Molecules; vol. 24; 5; (2019);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To an oven-dried screwed 20 mL vial were added (NHC)CuCl (c7 or c8, 0.2 mmol) suspended in dry THF (3 mL); in another vial, [tBu3PN]Li (1b, 42.3 mg, 0.95 eq.) was also dissolved in dry THF (3 mL), then the vial was put into glove-box fridge (-35 C) for one hour. Then the cold mixture was dropped into the (NHC)CuCl/THF suspension slowly under stirring and the suspension was turned into clear solution as the lithium salt added. After addition, the reaction mixture was kept at room temperature in glove box for 13 hours. After the reaction was completed, the volatile was removed under vacuum and dry hexane or pentane (7 mL) was added into the formed oily residue. The suspension obtained was kept stirring for another 15 mins at room temperature, then filtered through a short pad of neutral celite to get rid of precipitate. The filtrate was cooled down in the fridge (-35 C) for 3-4 hours to remove the unreacted lithium salt 1b further. Repeated once again to get the clear hexane or pentane filtrate. The filtrate was evaporated until white crystallized solid was formed, which is the catalytic active species (3 or 4). IPrCuCl (c7, 97 mg, 0.2 mmol); Obtain IPrCuNPtBu3 (3, 99 mg, 78%) as Colorless Solid; 1H NMR (C6D6, 600 MHz) delta 7.26-7.21 (br, m, 4H, m-ArH), 7.17-7.14 (br, m, 2H, p-ArH), 6.40 (s, 2H, NCH=), 2.83 (sep, 4H, J = 6.6 Hz, CH(CH3)2), 1.61 (d, 12H, J = 6.6 Hz, CH(CH3)2), 1.37 (d, 27H, J(PH) = 10.8 Hz, P(C(CH3)3)3), 1.20 (d, 12H, J = 6.6 Hz, CH(CH3)2); 13C NMR (C6D6, 151 MHz) delta 146.18, 136.50, 130.42, 128.68, 124.42, 122.05, 40.78, 40.49, 31.01, 29.33, 25.04, 24.42; 31P NMR (C6D6, 243 MHz) delta 26.35 (s); Elemental analysis calcd for [C39H63CuN3P+0.67 THF]: C, 69.84; H, 9.61; N, 5.86. Found: C, 69.48; H, 9.90; N, 6.19.

The synthetic route of 578743-87-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Bai, Tao; Yang, Yanhui; Han, Chao; Tetrahedron Letters; vol. 58; 15; (2017); p. 1523 – 1527;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride is a copper-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

In a flame-dried Schlenk tube under argon atmosphere, [CuCl(IPr)] (1) (0.3mmol, 150mg, 1 equiv.) and KCN (0.3mmol, 19mg, 1 equiv.) were introduced in degassed MeOH (5mL) and the reaction mixture was stirred under reflux (50C) for 4h. After returning to room temperature, the reaction mixture was concentrated to dryness under vacuum. The complex was then dissolved in dichloromethane and filtered through a pad of Celite and concentrated again under vacuum. A purification by recrystallization by slow diffusion of pentane in a THF solution of the complex led to the pure complex (4) as a white powder (143mg, 97% yield). 1H-NMR (CDCl3, 400MHz): delta 1.22 (d, J=6.9Hz, 12H), 1.27 (d, J=6.9Hz, 12H), 2.50 (sept, J=6.9Hz, 4H), 7.14 (s, 2H), 7.30 (d, J=7.8Hz, 4H), 7.50 (t, J=7.8Hz, 4H) ppm. (spectroscopic data in good agreement with the literature) [54].

As the paragraph descriping shows that 578743-87-0 is playing an increasingly important role.

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Article; Elie, Margaux; Mahoro, Gilbert Umuhire; Duverger, Eric; Renaud, Jean-Luc; Daniellou, Richard; Gaillard, Sylvain; Journal of Organometallic Chemistry; vol. 893; (2019); p. 21 – 31;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”