HPLC of Formula: 89396-94-1. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride, is researched, Molecular C20H28ClN3O6, CAS is 89396-94-1, about Antihypertensive effect of TA/6366, a new angiotensin-converting enzyme (ACE) inhibitor in two-kidney, one clip and one-kidney, one clip renovascular hypertensive rats.
Oral administration of TA/6366 (I), a new angiotensin-converting enzyme (ACE) inhibitor, decreased significantly mean arterial pressure in 2-kidney, 1 clip (2K1C) and 1-kidney, 1 clip (1K1C) renovascular hypertensive rats. The antihypertensive effect of I was almost as potent as that enalapril (II), but approx. 5 times more potent than that of captopril (III). The duration of action was almost similar among these 3 ACE inhibitors. The antihypertensive effect of I, II, or III was almost similar between in 2K1C and 1K1C, when they were treated with the same concentration I, II, and III had no substantial effect on the blood pressure in normal control rats. These results suggest that I is a potent antihypertensive agent in not only 2K1C but also 1K1C.
Although many compounds look similar to this compound(89396-94-1)HPLC of Formula: 89396-94-1, numerous studies have shown that this compound(SMILES:O=C([C@H](CN1C)N(C([C@@H](N[C@@H](CCC2=CC=CC=C2)C(OCC)=O)C)=O)C1=O)O.[H]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”