7787-70-4, A common heterocyclic compound, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route., 7787-70-4
A dry and Ar-flushed Schlenk flask was charged with P(OEt)3 (5.2 mL, 30.0 mmol) in benzene (30 mL). CuBr (4.3 g, 30.0 mmol) was added. After the mixture had stirred at r.t. for 1 h and at 80 C for 1 h, unsolved solid was removed by filtration under Ar atmosphere and solvents were evaporated from the filtrate. The resulted mixture was cooled down to -78 C and was washed with n-hexane (2*). The remained solid was dried under vacuum; this gave CuBr*P(OEt)3. Yield: 6.8 g (73%); a mixture of oil and solid.
With the rapid development of chemical substances, we look forward to future research findings about Copper(I) bromide
Reference£º
Article; Moriya, Kohei; Schwaerzer, Kuno; Karaghiosoff, Konstantin; Knochel, Paul; Synthesis; vol. 48; 19; (2016); p. 3141 – 3154;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”