Synthetic Route of C4H5BrO4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (S)-2-Bromosuccinic acid, is researched, Molecular C4H5BrO4, CAS is 20859-23-8, about Modified synthesis of (R)- and (S)-(2-benzyloxyethyl)oxirane from (S)- and (R)-aspartic acid. Author is Zhang, He-sheng; Kitching, William.
(R)- and (S)-(2-benzyloxyethyl)oxirane were prepared from (S)- and (R)-aspartic acid by modification of the procedure described by Rapoport. Aspartic acid was converted into bromosuccinic acid by treatment with sodium nitrite/potassium bromide/sulfuric acid,the diacid bromosuccinic acid was then reduced with freshly prepared boron trifluoride Et ether complex to bromodiol, which was further treated with sodium hydride and benzylbromide/TBAI (tetrabutylammonium iodide) to afford (2-benzyloxyethyl)oxirane. This procedure has shown the good yield, mild condition and excellent enantiomeric purity of the product.
In addition to the literature in the link below, there is a lot of literature about this compound((S)-2-Bromosuccinic acid)Synthetic Route of C4H5BrO4, illustrating the importance and wide applicability of this compound(20859-23-8).
Reference:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”