High enantioselectivity is induced by a single monodentate phosphoramidite ligand in iridium-catalyzed asymmetric hydrogenation was written by Giacomina, Francesca;Meetsma, Auke;Panella, Lavinia;Lefort, Laurent;de Vries, Andre H. M.;de Vries, Johannes G.. And the article was included in Angewandte Chemie, International Edition in 2007.Computed Properties of C24H34O2 This article mentions the following:
Stripping a catalyst down to its bare essentials makes a neutral iridium complex, containing only one monodentate phosphoramidite ligand, an efficient catalyst for the enantioselective hydrogenation of α-dehydroamino acids. For example, neutral iridium chiral catalyst [Ir(COD)(L)Cl], where L = (S)-(3,3′-di-tert-butyl-5,5′,6,6′-tetramethyl-1,1′-biphenyl-2,2′-diyl)-N,N-dimethylphosphoramidite (I), is an effective catalyst for the asym. hydrogenation of PhCH:C(NHCOMe)CO2Me to N-acetylphenylalaninate Me ester. In the experiment, the researchers used many compounds, for example, (S)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol (cas: 205927-03-3Computed Properties of C24H34O2).
(S)-3,3′-Di-tert-butyl-5,5′,6,6′-tetramethylbiphenyl-2,2′-diol (cas: 205927-03-3) belongs to copper catalysts. Copper catalyst has received great attention owing to the low toxicity and low cost. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Computed Properties of C24H34O2
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”