In vitro pesticides susceptibility of Erwinia sp. causing papaya (Carica papaya) black rot in Okinawa, Japan and captan effectiveness on papaya pot seedlings was written by Hanagasaki, Takashi;Takushi, Tetsuya;Kawano, Shinji;Yamashiro, Maki. And the article was included in Journal of General Plant Pathology in 2022.Formula: CuH2O2 This article mentions the following:
Since 2002, papaya black rot has been spreading over several islands of Okinawa Prefecture. The pathogen of the disease was identified as Erwinia sp., genetically close to E. mallotivora and E. papayae. In terms of the disease transmission, it is probably carried by the wind or rain. In order to devise a prevention strategy for the disease, in vitro pesticides susceptibility of the pathogen and tests with papaya pot seedlings were conducted. A min. inhibitory concentration assay demonstrated that copper (II) hydroxide, basic copper sulfate, and captan present in the papaya-registered pesticides inhibited the growth of the pathogen on nutrient agar plates. In addition, mancozeb that is non-papaya-registered pesticide also showed an inhibitory effect on the pathogen. Thus, there is a high possibility that even the existing papaya-registered or non-papaya-registered pesticides can prevent papaya black rot. In the test with papaya pot seedlings, copper (II) hydroxide exerted a relatively lower pesticide effect; however, captan exhibited a pesticide effect, although it is one of the fungicides not registered for use in the treatment of bacterial diseases of plants in Japan till date. Indeed, based on the result of the present study, the official registration of legal expansion for use of captan to control papaya black rot was approved in Japan on Dec. 22, 2021. In the experiment, the researchers used many compounds, for example, Cuprichydroxide (cas: 20427-59-2Formula: CuH2O2).
Cuprichydroxide (cas: 20427-59-2) belongs to copper catalysts. The transition metal-catalyzed chemical transformation of organic electrophiles and organometallic reagents has turned up as an exceedingly robust synthetic tool. These ligands enable the reaction promoted in mild condition. The reaction scope has also been greatly expanded, rendering this copper-based cross-coupling attractive for both academia and industry. Formula: CuH2O2
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”