Haskali, Mohammad B. et al. published their research in Molecules in 2022 | CAS: 34946-82-2

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to low toxicity and inexpensive, earth-abundant. Copper of different valence states can be used to catalyze the coupling reaction, especially the Ullmann coupling reaction. Formula: C2CuF6O6S2

Effective Preparation of [18F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor was written by Haskali, Mohammad B.;Roselt, Peter D.;O’Brien, Terence J.;Hutton, Craig A.;Ali, Idrish;Vivash, Lucy;Jupp, Bianca. And the article was included in Molecules in 2022.Formula: C2CuF6O6S2 This article mentions the following:

[18F]Flumazenil 1 ([18F]FMZ) is an established positron emission tomog. (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABAA in the brain. The production of [18F]FMZ 1 for its clin. use has proven to be challenging, requiring harsh radiochem. conditions, while affording low radiochem. yields. Fully characterized, new methods for the improved production of [18F]FMZ 1 are needed. We investigate the use of late-stage copper-mediated radiofluorination of aryl stannanes to improve the production of [18F]FMZ 1 that is suitable for clin. use. Mass spectrometry was used to identify the chem. byproducts that were produced under the reaction conditions. The radiosynthesis of [18F]FMZ 1 was fully automated using the iPhase FlexLab radiochem. module, affording a 22.2 ± 2.7% (n = 5) decay-corrected yield after 80 min. [18F]FMZ 1 was obtained with a high radiochem. purity (>98%) and molar activity (247.9 ± 25.9 GBq/μmol). The copper-mediated radiofluorination of the stannyl precursor is an effective strategy for the production of clin. suitable [18F]FMZ 1. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Formula: C2CuF6O6S2).

Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The applications of Copper-based nanoparticles have received great attention due to low toxicity and inexpensive, earth-abundant. Copper of different valence states can be used to catalyze the coupling reaction, especially the Ullmann coupling reaction. Formula: C2CuF6O6S2

Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”