In 2019,Acta Crystallographica, Section C: Structural Chemistry included an article by Moncol, Jan; Mazur, Milan; Valko, Marian; Choi, Jong-Ha. COA of Formula: Br2Cu. The article was titled 《Synthesis, structural characterization, EPR spectroscopy and Hirshfeld surface analysis of a novel Cu2+-doped 3,14-diethyl-2,13-diaza-6,17-diazoniatricyclo[16.4.0.07,12]docosane bis(perchlorate)》. The information in the text is summarized as follows:
Cyclam derivatives and their metal complexes have been found to exhibit an anti-HIV effect and stimulate the activity of stem cells from bone marrow. The strength of their binding to the CXCR4 receptor correlates with anti-HIV and stem-cell activities. Knowledge of the conformation and crystal packing of various macrocyclic metal complexes has become important in developing new effective anti-HIV drugs. The synthesis and preparation of single crystals of a new Cu2+-doped macrocyclic compound, (3,14-diethyl-2,6,13,17-tetraazatricyclo[16.4.0.07,12]docosane)copper(II) bis(perchlorate)-3,14-diethyl-2,13-diaza-6,17-diazoniatricyclo[16.4.0.07,12]docosane bis(perchlorate) (0.69/0.31), {[Cu(C22H44N4)](ClO4)2}0.69·(C22H46N42+·2ClO4-)0.31, is reported. Characterization by X-ray diffraction anal. shows that the asym. unit contains half of a centrosym. mol. The macrocyclic ligand in the compound adopts the most stable trans-III conformation. The Cu-N distances of 2.015 (3) and 2.047 (3) Å are normal, but the long axial Cu-O bond of 2.795 (3) Å may be due to a combination of the Jahn-Teller effect and the strong in-plane ligand field. The crystal structure is stabilized by hydrogen bonding between secondary N-H groups, the N atoms of the macrocycle and the O atoms of the perchlorate anions. After reading the article, we found that the author used Cupric bromide(cas: 7789-45-9COA of Formula: Br2Cu)
Some reported applications of Cupric bromide(cas: 7789-45-9) are: catalyst in cross coupling reactions; co-catalyst in Sonogashira coupling; lewis acid in enantioselective addition of alkynes.COA of Formula: Br2Cu
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”