Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Recommanded Product: 18742-02-4, 18742-02-4, Name is 2-(2-Bromoethyl)-1,3-dioxolane, molecular formula is C5H9BrO2, belongs to copper-catalyst compound. In a document, author is Asgari, Mohammad Sadegh, introduce the new discover.
Copper-catalyzed one-pot synthesis of amide linked 1,2,3-triazoles bearing aryloxy skeletons
In this paper, novel amide linked 1,2,3-triazoles containing aryloxy derivatives (8a-l) are synthesized via copper-catalyzed one-pot sequential hydroxylation-O-alkylation/click reaction of 2-bromo-N-prop-2-ynyl-benzamides. The products are synthesized in an efficient way in high isolated yields. The synthetic method involves the use of 2-bromo-N-prop-2-ynyl-benzamide and various benzyl halides over a onepot copper-catalyzed hydroxylation-O-alkylation/Click reaction. The products are characterized by H-1 NMR, C-13 NMR, mass spectrometry, FT-IR, elemental analysis, melting point, and single crystal X-ray diffraction. In-situ prepared phenol moiety in H2O/DMF as a solvent co-solvent system prompted to perform a reaction between benzyl halide and phenols. The step economic feature of the method leads to the synthesis of the products in high isolated yields. (C) 2020 Published by Elsevier Ltd.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 18742-02-4. Recommanded Product: 18742-02-4.
Reference:
Copper catalysis in organic synthesis – NCBI,
,Special Issue “Fundamentals and Applications of Copper-Based Catalysts”