Acid-Catalyzed Decomposition of O-Silylated α-Diazo-β-hydroxy Esters: Access to Mixed Monosilyl Acetals was written by Rouzier, Florian;Montiege, Ophelie;Lhoste, Jerome;Gaulon-Nourry, Catherine;Castanet, Anne-Sophie;Chany, Anne-Caroline. And the article was included in Journal of Organic Chemistry in 2022.Synthetic Route of C2CuF6O6S2 This article mentions the following:
Acid-catalyzed decomposition of diazocarbonyl compounds triggers a wide range of transformations leading to synthetically useful building blocks with high diversity. In this field, the chem. of α-diazo-β-hydroxy ester substrates is largely dominated by migration processes. The authors describe herein a new approach to original mixed monosilyl acetals from O-protected α-diazo-β-hydroxy-β-aryl esters and alcs., catalyzed by trimethylsilyl trifluoromethanesulfonate (TMSOTf). The ratio between these original mixed acetals, the sym. acetals, and the migration products fluctuates depending on the catalyst, the nature of the alcs., and the substituent on the aromatic ring. Fifty-six examples are reported herein with yields up to 71% and diastereoselectivity up to 6:1. Such mixed monosilyl acetals constitute a synthetic equivalent of α-substituted β-oxoesters with high potential for further transformations. In the experiment, the researchers used many compounds, for example, Copper(II) trifluoromethanesulfonate (cas: 34946-82-2Synthetic Route of C2CuF6O6S2).
Copper(II) trifluoromethanesulfonate (cas: 34946-82-2) belongs to copper catalysts. The evolution of transition metal catalysts has attained a stage of civilization that authorizes for an extensive scope of chemical bonds formation partners to be combined efficiently. Due to these characteristics, copper nanoparticles have generated a great deal of interest especially in the field of catalysis. Synthetic Route of C2CuF6O6S2
Referemce:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”