Tag: M.W:400-500

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

In a glovebox, a 30 mL round-bottom flask was charged with (IPr)CuCl (969.0 mg, 2.00 mmol) and NaOtBu (192.0 mg, 2.00 mmol). Anhydrous THF (12.0 mL) was added. The resulting opaque brown solution was stirred for 2.0 h. It was filtered through Celite in glovebox and concentrated in vacuo affording (IPr)Cu(OtBu) as an off-white powder (802.2 mg, 79% yield).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, 578743-87-0

Reference£º
Article; Zeng, Wei; Wang, Enyu; Qiu, Rui; Sohail, Muhammad; Wu, Shaoxiang; Chen, Fu-Xue; Journal of Organometallic Chemistry; vol. 743; (2013); p. 44 – 48;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

In a glove box, IPrCuCl (100 mg, 0.205 mmol) and potassium tris (3,5 – dimethyl – 1 – pyrazolyl) borohydride (76.3mg, mmol) in THF in a 20 mixture was stirred at room temperature for 5 hours to dongan It was. Filtered through a plug of after the reaction mixture was Celite and the solvent was evaporated under reduced pressure to give product IPrCuTp * as a white powder

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, 578743-87-0

Reference£º
Patent; University Of Southern California; Thompson, Mark E; Hamz, Rasya; Durovitch, Peter I; (50 pag.)KR2015/26932; (2015); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

In a dry double-mouth bottle to place Pt – 2 (0.0594 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.047 g, and the yield is 40%.

The chemical industry reduces the impact on the environment during synthesis,578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,I believe this compound will play a more active role in future production and life.

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

It is a common heterocyclic compound, the copper-catalyst compound, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0 its synthesis route is as follows.

In a dry double-mouth bottle to place Pt – 1 (0.0544 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.045 g, and the yield is 40%.

578743-87-0, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,578743-87-0 ,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Cu(I)-NHC 1a-g (0.04 mmol, 1.0 equiv) and CDCl3 (0.4 mL, degassed by bubbling argon for 30 min) were added into a flame-dried NMR tube. (CD3)2SO (0.4 mL) was used for 1h (0.04 mmol), 1i (0.02 mmol), and 1j (0.02 mmol). The NMR tube was closed with a septum and equipped with an air balloon (approximate 500 mL) containing approximately 100 mL of O2 (4.5 mmol, 112 equiv.) and approximately 12.6 mL of H2O (gas, 0.56 mmol, 14 equiv., air relative humidity = 75%). The solution (not agitated) was placed at room temperature and was monitored by 1H NMR. 100 C was used for the decomposition of 1h, and 150 C was used for the decomposition of 1i and 1j. The precipitate in the NMR tube was removed by quick filtration using a membrane filter before each 1H NMR measurement. The ratio of Cu-NHC, urea, and imidazolium were calculated through the integration of 1H NMR, using the normalization method. The characterization of products could be found in the previous study [32].

The chemical industry reduces the impact on the environment during synthesis,578743-87-0,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Li, Dazhi; Ollevier, Thierry; Journal of Organometallic Chemistry; vol. 906; (2020);,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, and cas is 578743-87-0, its synthesis route is as follows.

In a dry double-mouth bottle to place Ir – 2 (0.0796 g, 0.1 mmol), CuClNHC (0.0488 g, 0.1 mmol), vacuum pumping and nitrogen cycle three times, then the nitrogen flow by adding 10 ml ethanol, stirring reflux reaction for 4 hours, cooling to room temperature, then added potassium hexafluorophosphate (0.184 g, 1 mmol), stirring at the room temperature reaction 2 hours, filtered, concentrated filtrate, ethanol: dichloromethane=1:10 column, get the orange solid 0.069 g, and the yield is 50%.

578743-87-0, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,578743-87-0 ,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Jiangsu University Of Science And Technology; Shi Chao; Li Qiuxia; Zhang Xinghua; (24 pag.)CN108690096; (2018); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

As a common heterocyclic compound, it belongs to copper-catalyst compound, name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, and cas is 578743-87-0, its synthesis route is as follows.,578743-87-0

1) 0.2 mmol (NHC) CuCl was dissolved in 3 ml of dry THF in a 20 ml dry glass bottle to form a suspension,The glass was then placed in a glove box refrigerator and frozen at -35 C for 1 h;2) 42.3 mg (0.95 eq) [tBu3PN] Li was dissolved in 3 ml of dry THF in another 20 ml dry glass vial,And then put the glass bottle into the glove box refrigerator,Frozen at -35 C for 1 h;3) Slowly drop the [tBu3PN] Li solution of 2) in a cold (NHC) CuCl suspension in 1) with stirring,After completion of the dropwise addition, the mixture was stirred in a glove box at room temperature for 13 h;4) After completion of the reaction, the solvent (THF) was dried in vacuo to give an oily slag,Followed by the addition of 7 ml of n-pentane or n-hexane to give a suspension,And stirred at room temperature for 15 min,And then through the neutral diatomite short pad filter to remove insoluble matter,The filtrate was placed in a refrigerator and cooled at -35 C for 3-4 h,And then filtered through neutral diatomaceous earth,And then frozen the filtrate,Repeated several times to obtain a clear n-pentane or n-hexane solution,The clear solution was dried to give a white crystalline solid,Ie complex A or B.

With the complex challenges of chemical substances, we look forward to future research findings about 578743-87-0,belong copper-catalyst compound

Reference£º
Patent; Shan, Xida; Bai, Tao; Yang, Yanhui; (31 pag.)CN106243132; (2016); A;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

Name is [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, as a common heterocyclic compound, it belongs to copper-catalyst compound, and cas is 578743-87-0, its synthesis route is as follows.

Chloro[l ,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (121.9 mg, 0.25 mmol) and silver triflate (64.2 mg, 0.25 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes. Solution of 1 , 10-phenanthroline (45.05 mg, 0.25 mmol) in dry THF (5 mL) was added. Reaction mixture turned yellow and was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2Ch by vapor diffusion of Et20 gave 120 mg (61.4%) of yellow crystals. Anal, calcd. for C40H44CUF3N4O3S: C, 61.48; H, 5.68; N, 7.17; Found: C, 61.06; H, 5.61; N, 7.14. Structure was confirmed by IH-NMR spectrum of [(IPR)Cu(phen)]OTf (CDCb, 400MHz).

578743-87-0, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,578743-87-0 ,[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

Chloro[l,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (195.1 mg, 0.4 mmol) and silver triflate (102.7 mg, 0.4 mmol) were mixed under nitrogen in 25 mL flask and 10 mL of dry THF were added. Reaction mixture was stirred at RT for 30 minutes.Solution of 2,2′-bipyridine (62.4 mg, 0.4 mmol) in dry THF (5 mL) was added. Reaction mixture turned orange and was stirred at RT overnight. Resulting mixture was filtered through Celite and solvent was evaporated on rotovap. Recrystallization from CH2CI2 by vapor diffusion of EtaO gave 215 mg (70.9%) of orange crystals. Anal, calcd. forC38H44CUF3N4O3S: C, 60.26; H, 5.86; N, 7.40; Found: C, 60.18; H, 5.82; N, 7.38. Structure was confirmed by iH-NMR spectrum of [(IPR)Cu(bipy)]OTf (CDCb, 400MHz).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, 578743-87-0

Reference£º
Patent; THE UNIVERSITY OF SOUTHERN CALIFORNIA; THOMPSON, Mark; DJUROVICH, Peter; KRYLOVA, Valentina; WO2011/63083; (2011); A1;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”

578743-87-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, cas is 578743-87-0,the copper-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: To an oven-dried screwed 20 mL vial were added (NHC)CuCl (c7 or c8, 0.2 mmol) suspended in dry THF (3 mL); in another vial, [tBu3PN]Li (1b, 42.3 mg, 0.95 eq.) was also dissolved in dry THF (3 mL), then the vial was put into glove-box fridge (-35 C) for one hour. Then the cold mixture was dropped into the (NHC)CuCl/THF suspension slowly under stirring and the suspension was turned into clear solution as the lithium salt added. After addition, the reaction mixture was kept at room temperature in glove box for 13 hours. After the reaction was completed, the volatile was removed under vacuum and dry hexane or pentane (7 mL) was added into the formed oily residue. The suspension obtained was kept stirring for another 15 mins at room temperature, then filtered through a short pad of neutral celite to get rid of precipitate. The filtrate was cooled down in the fridge (-35 C) for 3-4 hours to remove the unreacted lithium salt 1b further. Repeated once again to get the clear hexane or pentane filtrate. The filtrate was evaporated until white crystallized solid was formed, which is the catalytic active species (3 or 4). IPrCuCl (c7, 97 mg, 0.2 mmol); Obtain IPrCuNPtBu3 (3, 99 mg, 78%) as Colorless Solid; 1H NMR (C6D6, 600 MHz) delta 7.26-7.21 (br, m, 4H, m-ArH), 7.17-7.14 (br, m, 2H, p-ArH), 6.40 (s, 2H, NCH=), 2.83 (sep, 4H, J = 6.6 Hz, CH(CH3)2), 1.61 (d, 12H, J = 6.6 Hz, CH(CH3)2), 1.37 (d, 27H, J(PH) = 10.8 Hz, P(C(CH3)3)3), 1.20 (d, 12H, J = 6.6 Hz, CH(CH3)2); 13C NMR (C6D6, 151 MHz) delta 146.18, 136.50, 130.42, 128.68, 124.42, 122.05, 40.78, 40.49, 31.01, 29.33, 25.04, 24.42; 31P NMR (C6D6, 243 MHz) delta 26.35 (s); Elemental analysis calcd for [C39H63CuN3P+0.67 THF]: C, 69.84; H, 9.61; N, 5.86. Found: C, 69.48; H, 9.90; N, 6.19.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper chloride, 578743-87-0

Reference£º
Article; Bai, Tao; Yang, Yanhui; Han, Chao; Tetrahedron Letters; vol. 58; 15; (2017); p. 1523 – 1527;,
Copper catalysis in organic synthesis – NCBI
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”