Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Safety of Bis(acetylacetone)copper, Name is Bis(acetylacetone)copper, molecular formula is C10H16CuO4, Safety of Bis(acetylacetone)copper, In a Article, authors is Reddy, Angula Chandra Shekar£¬once mentioned of Safety of Bis(acetylacetone)copper
Copper catalyzed oxidative coupling of ortho-vinylanilines with N-tosylhydrazones: Efficient synthesis of polysubstituted quinoline derivatives
Efficient and general copper catalyzed oxidative cyclization of ortho-vinylaniline has been accomplished employing N-tosylhydrazone as coupling partner. Various substituted quinoline derivatives of biological importance were achieved in good to excellent yield. The important features are the high functional group tolerates, up-gradation to gram scale synthesis and possible one-pot synthesis of quinoline from corresponding carboxaldehyde. Synthetic potential of the obtained quinoline derivatives was demonstrated through C-H bond functionalization reaction. Furthermore, preliminary mechanistic investigation revealed the possible generation of non-stabilized diazo compound and imine derivative as potential intermediates as well as copper catalyzed electrocyclic reaction and oxidative aromatization.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Safety of Bis(acetylacetone)copper, you can also check out more blogs aboutSafety of Bis(acetylacetone)copper
Reference£º
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”