So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Guerin, Philippe; Vert, Michel; Braud, Christian; Lenz, Robert W. researched the compound: (S)-2-Bromosuccinic acid( cas:20859-23-8 ).Synthetic Route of C4H5BrO4.They published the article 《Optically active poly(β-malic acid)》 about this compound( cas:20859-23-8 ) in Polymer Bulletin (Berlin, Germany). Keywords: polymalic acid optical activity; polybenzyl malate hydrolysis. We’ll tell you more about this compound (cas:20859-23-8).
Optically active benzyl malolactonate [99494-21-0] was prepared starting from L-aspartic acid [56-84-8] and polymerized anionically using Et3N as initiator to yield poly(benzyl β-malate) [99438-25-2] which is an optically active, semicrystalline polymer. Cleavage of protecting benzyl ester groups yielded optically active poly(β-malic acid) [99438-26-3] which showed 1 accessible pos. CD band in the far UV.
There is still a lot of research devoted to this compound(SMILES：O=C(O)[C@@H](Br)CC(O)=O)Synthetic Route of C4H5BrO4, and with the development of science, more effects of this compound(20859-23-8) can be discovered.
Reference:
Copper catalysis in organic synthesis – NCBI,
Special Issue “Fundamentals and Applications of Copper-Based Catalysts”